TH88617A - Histamine-3 receptor antagonist - Google Patents

Abstract

DC60 (22/01/50) invention of this Concerning the compounds of formula I, (chemical formula) I as defined herein, or the salts of those substances that are accepted on a pharmaceutical basis; Pharmaceutical mixtures containing formula I compounds, formula I compound preparation processes, remedies for abnormalities or conditions that may be treated by antagonized histamine H3 receptors, which The combined method is by giving the compound of Formula I described above to mammals. As required Of such treatments, and how to treat the disorder Or a state selected from a group containing Depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, hyperactivity disorder (ADHD), mental disorders, Perceptual disorders, Sleep disorders, Obesity, Dizziness, Epilepsy, Motion sickness, Respiratory disorder, Allergy, Airway response at Induced by allergic, allergic rhinitis, nasal congestion, congestion, congestion, hypotension, coronary heart disease, gastrointestinal tract disease, spontaneous movement, and Gastrointestinal secretion of the gastrointestinal tract, which consists in providing mammals the compound of Formula I described above, to mammals the need for such treatment. This invention Concerning the compounds of formula I, (chemical formula) I as defined herein, or the salts of those substances that are accepted on a pharmaceutical basis; Pharmaceutical mixtures containing formula I compounds, formula I compound preparation processes, remedies for abnormalities or conditions that may be treated by antagonized histamine H3 receptors, which The combined method is by giving the compound of Formula I described above to mammals. As required Of such treatments, and how to treat the disorder Or a state selected from a group containing Depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, hyperactivity disorder (ADHD), mental disorders, Perceptual disorders, Sleep disorders, Obesity, Dizziness, Epilepsy, Motion sickness, Respiratory disorder, Allergy, Airway response at Induced by allergic, allergic rhinitis, nasal congestion, congestion, congestion, hypotension, coronary heart disease, gastrointestinal tract disease, spontaneous movement, and Gastrointestinal secretion of the gastrointestinal tract, which consists in providing the compound of Formula I described above, to mammals according to the therapeutic requirements.

Claims (1)

1. Compounds of formula I (chemical formula) I or salts of those substances that are well tolerated by pharmacology, in which: R1 and R2 are selected independently from the hydrogen group; C1-C8 selected alkyls are replaced with 1 to 4 halogen atoms; The C1-C4 selected alkyl groups were replaced with the selected substitutes from the OH group, one to four groups of C1-C4 alkyl, C3-C7 Cyotoxic: Drug patent.