TH88289B - Piperazine with a group of metabolites containing metabolites, glucose receptors, antagonists. - Google Patents
Piperazine with a group of metabolites containing metabolites, glucose receptors, antagonists.Info
- Publication number
- TH88289B TH88289B TH1401001344A TH1401001344A TH88289B TH 88289 B TH88289 B TH 88289B TH 1401001344 A TH1401001344 A TH 1401001344A TH 1401001344 A TH1401001344 A TH 1401001344A TH 88289 B TH88289 B TH 88289B
- Authority
- TH
- Thailand
- Prior art keywords
- metabolites
- piperazine
- antagonists
- group
- alkyl
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
- 239000002207 metabolite Substances 0.000 title 2
- 239000005557 antagonist Substances 0.000 title 1
- 108010070004 glucose receptor Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 230000000423 heterosexual effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract 2
- 102000012777 Metabotropic Glutamate 5 Receptor Human genes 0.000 abstract 1
- 108010065028 Metabotropic Glutamate 5 Receptor Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบของสูตร I หรือเกลือหรือโซลเวตของสารเหล่านั้นที่ ยอมรับได้ทางยา (สูตรเคมี) (I) ซึ่ง Ar1, Ar2, Hy, L, R1, m และ n เป็นดังกำหนดไว้ในการบรรยาย การประดิษฐ์นี้ยังรวมถึงสารผสมที่ เป็นยาและการใช้งานของสารเหล่านั้น, กระบวนการทำสารประกอบดังกล่าว, รวมทั้งวิธีการสำหรับ การบำบัดความผิดปรกติที่สื่อกลางด้วย mGluR5 ในทางการแพทย์: The present invention relates to compounds of formula I or salts or solvates thereof that Medicinally acceptable (chemical formula) (I) where Ar1, Ar2, Hy, L, R1, m and n are as defined in the lecture. The invention also includes mixtures that as medicine and the uses of those substances, the process of making such compounds, including methods for Clinical treatment of mGluR5 mediated disorders:
Claims (1)
Publications (3)
Publication Number | Publication Date |
---|---|
TH88289B true TH88289B (en) | 2008-01-31 |
TH152908A TH152908A (en) | 2016-06-09 |
TH1401001344B TH1401001344B (en) | 2016-06-09 |
Family
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