TH8805A - Various 3-aryloxin-methyl cephalosporin derivatives, preparations of these substances and their medicinal use. - Google Patents
Various 3-aryloxin-methyl cephalosporin derivatives, preparations of these substances and their medicinal use.Info
- Publication number
- TH8805A TH8805A TH8901001035A TH8901001035A TH8805A TH 8805 A TH8805 A TH 8805A TH 8901001035 A TH8901001035 A TH 8901001035A TH 8901001035 A TH8901001035 A TH 8901001035A TH 8805 A TH8805 A TH 8805A
- Authority
- TH
- Thailand
- Prior art keywords
- group
- substances
- various
- aryloxin
- preparations
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 3
- 239000000758 substrate Substances 0.000 claims abstract 3
- 229940079593 drug Drugs 0.000 claims abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 2
- -1 C1-C10 group Chemical group 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical group C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000191940 Staphylococcus Species 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229960003085 meticillin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Abstract
สารประกอบที่มีสูตร (I)##สูตรทางเคมี ซึ่ง R ยกกำลัง 1 คือไฮโดรเจนหรือแอซิล, R ยกกำลัง 2 คือ ไฮโดรเจน หรือ C1-C4 แอลคอกซิ, และ Ar คือเฟนิลหรือซับสทิ ทิวเทดเฟนิล และเกลือและเอสเทอร์ต่าง ๆ ของสารนั้นที่ยอมรับทาง เภสัชกรรมมีการแสดงฤทธิ์เชิงปฏิชีวนะที่มีคุณค่า, รวมไปถึงการ ต่อต้าน Methicillin-resistant strains ของ Staphylococcus การประดิษฐ์ยังจัดหากรรมวิธีสำหรับการเตรียมสารประกอบต่าง ๆ และวิธีหลายวิธีและสารผสมที่ใช้สารประกอบเหล่านี้ : สิทธิบัตรยา Compound with formula (I) ## Chemical formula where R to the power of 1 is hydrogen or azyl, R to the second power is hydrogen or C1-C4 alcoxin, and Ar is phenyl or substrate phenyl and Salts and esters of substances that accept Pharmaceuticals have shown valuable antibiotic activity, including anti-methicillin-resistant strains of Staphylococcus. The invention also provides methods for the preparation of various compounds and methods and mixtures that use these compounds: drug patents.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH8805A true TH8805A (en) | 1991-05-01 |
Family
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