TH84864B - Antibody formula - Google Patents
Antibody formulaInfo
- Publication number
- TH84864B TH84864B TH501004920A TH0501004920A TH84864B TH 84864 B TH84864 B TH 84864B TH 501004920 A TH501004920 A TH 501004920A TH 0501004920 A TH0501004920 A TH 0501004920A TH 84864 B TH84864 B TH 84864B
- Authority
- TH
- Thailand
- Prior art keywords
- antibody formula
- antibody
- formula
- antibodies
- histidine
- Prior art date
Links
- 108090001123 antibodies Proteins 0.000 title claims abstract 9
- 102000004965 antibodies Human genes 0.000 title claims abstract 9
- HABAJMUFCIDFOT-JEDNCBNOSA-M (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;acetate Chemical compound CC([O-])=O.OC(=O)[C@@H](N)CC1=CN=CN1 HABAJMUFCIDFOT-JEDNCBNOSA-M 0.000 claims abstract 3
- 239000008351 acetate buffer Substances 0.000 claims abstract 3
- UIIMBOGNXHQVGW-UHFFFAOYSA-M buffer Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- BZWQQOVSUSJJJO-QAGDRQIHSA-N 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4H-[1,3]thiazolo[4,5-d]pyrimidine-2,7-dione;hydrate Chemical compound O.O=C1SC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O BZWQQOVSUSJJJO-QAGDRQIHSA-N 0.000 abstract 1
- 102100016662 ERBB2 Human genes 0.000 abstract 1
- 101700025368 ERBB2 Proteins 0.000 abstract 1
- 101710037934 QRSL1 Proteins 0.000 abstract 1
- 229960000070 antineoplastic Monoclonal antibodies Drugs 0.000 abstract 1
- 108010048040 apomab Proteins 0.000 abstract 1
- 108010045030 monoclonal antibodies Proteins 0.000 abstract 1
- 229960000060 monoclonal antibodies Drugs 0.000 abstract 1
- 102000005614 monoclonal antibodies Human genes 0.000 abstract 1
Abstract
การประยุกต์ใช้ที่มีอยู่อธิบายถึงสูตรแอนติบอดีซึ่งประกอบด้วยแอนติบอดีชนิดโมโนโคลนัล ผลิตตามสูตรในบัฟเฟอร์ชนิดฮิสติดีน-อะซิเทตรวมไปถึงสูตรประกอบไปด้วยแอนติบอดีชนิดซึ่งเชื่อม ต่อเข้ากับโดเมน II ของ HER2 (ตัวอย่างเช่นเปอร์ทูซูแมบ) และสูตรประกอบไปด้วยแอนติบอดีชนิด ซึ่งเชื่อมต่อเข้ากับ DR5 (ตัวอย่างเช่นอะโพแมบ) An existing application describes an antibody formulation consisting of monoclonal antibodies. It is formulated in histidine-acetate buffer, including the formulation of antibodies. It is attached to the domain II of HER2 (for example, supertosumab) and the formula contains antibodies. Which is connected to the DR5 (for example, apomab)
Claims (4)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH84864A TH84864A (en) | 2007-06-07 |
| TH84864B true TH84864B (en) | 2007-06-07 |
Family
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