TH83129B - Compounds (aryl amidauryl) - quadramide - Google Patents
Compounds (aryl amidauryl) - quadramideInfo
- Publication number
- TH83129B TH83129B TH501004355A TH0501004355A TH83129B TH 83129 B TH83129 B TH 83129B TH 501004355 A TH501004355 A TH 501004355A TH 0501004355 A TH0501004355 A TH 0501004355A TH 83129 B TH83129 B TH 83129B
- Authority
- TH
- Thailand
- Prior art keywords
- cancer
- tumors
- leukemia
- cells
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 5
- 125000003118 aryl group Chemical group 0.000 title claims 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitrogen oxide Inorganic materials O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims abstract 6
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 238000006073 displacement reaction Methods 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract 6
- 201000011510 cancer Diseases 0.000 abstract 4
- 208000032839 leukemia Diseases 0.000 abstract 4
- 230000001154 acute effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000004698 lymphocyte Anatomy 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- 206010014733 Endometrial cancer Diseases 0.000 abstract 1
- 206010014759 Endometrial neoplasm Diseases 0.000 abstract 1
- 206010061535 Ovarian neoplasm Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 206010042971 T-cell lymphoma Diseases 0.000 abstract 1
- 208000027585 T-cell non-Hodgkin lymphoma Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 208000024313 Testicular Neoplasms Diseases 0.000 abstract 1
- 208000024770 Thyroid neoplasm Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000002534 adenoid Anatomy 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 208000035250 cutaneous malignant susceptibility to 1 melanoma Diseases 0.000 abstract 1
- 208000031513 cyst Diseases 0.000 abstract 1
- 210000002249 digestive system Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002357 endometrial effect Effects 0.000 abstract 1
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 abstract 1
- 201000001142 lung small cell carcinoma Diseases 0.000 abstract 1
- 201000006512 mast cell neoplasm Diseases 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 210000003928 nasal cavity Anatomy 0.000 abstract 1
- 201000005837 nasal cavity lymphoma Diseases 0.000 abstract 1
- 208000025189 neoplasm of testis Diseases 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 201000006845 reticulosarcoma Diseases 0.000 abstract 1
- 208000029922 reticulum cell sarcoma Diseases 0.000 abstract 1
- 208000000649 small cell carcinoma Diseases 0.000 abstract 1
- 208000000587 small cell lung carcinoma Diseases 0.000 abstract 1
- 201000003120 testicular cancer Diseases 0.000 abstract 1
- 201000002510 thyroid cancer Diseases 0.000 abstract 1
Abstract
สารประกอบที่แสดงให้เห็นตามสูตร (I) นั้นคือ (สูตรเคมี) (I) หรือเกลือเวชภัณฑ์ชนิดที่ยอมรับได้หรือออกไซด์ไนโตรเจนของสารประกอบเหล่านั้นโดยที่ A, Q, Y, R5, m และ J เป็นตามที่ได้กำหนดไว้ ณ ที่นี้ซึ่งนำมาใช้ในการบัดรักษาเนื้องอกและโรค มะเร็งดังเช่นภาวะมีมาสต์เซลล์ในเนื้อเยื้อ/มะเร็งเม็ดเลือกขาวในมาสต์เซลล์ เนื้องอกภายในเนื้อเยื่อ ค้ำของระบบย่อยอาหาร (GIST) เนื้องอกในเซลล์อ่อน มะเร็งเซลล์ขนาดเล็กภายในปอด (SCLC) มะเร็งเซลล์น้ำเหลืองของตัวฆ่าที่มีอยู่ตามธรรมชาติในโพรงจมูก/มะเร็งเซลล์น้ำเหลืองใน T-เซลล์ มะเร็งอัณฑะ (เนื้องอกที่อัณฑะ) มะเร็งต่อมไธรอยด์ มะเร็งเม็ดสีเมลาโนมาขึ้นร้ายแรง เนื้องอกใน รังไข่ มะเร็งจากก้อนซีสต์ในต่อมแอ็ดดินอยด์ มะเร็งเม็ดเลือดขาวในไขกระดูกระยะเฉียบพลัน (AML) มะเร็งเต้านม มะเร็งเม็ดเลือกขาวของเซลล์น้ำเหลืองจาก T-เซลล์ในเด็กระยะเฉียบพลัน มะเร็งของระบบประสาท มะเร็งเม็ดเลือดขาวในมาสต์เซลล์ มะเร็งเนื้อเยื่อชนิดแอนจิโอมา มะเร็ง ตอมน้ำเหลืองของเซลล์ขนาดใหญ่ผิดปกติ มะเร็งเยื้อบุมดลูกและมะเร็งต่อมลูกหมาก The compounds shown by the formula (I) are (chemical formula) (I) or acceptable pharmaceutical salts or nitrogen oxides of those compounds where A, Q, Y, R5, m and J are defined. Listed here that are used in the treatment of tumors and diseases. Cancer, such as mantleous mantleemia / leukemia in mast cell Tumors within the tissue Support of the digestive system (GIST) tumors in young cells. Lung small cell carcinoma (SCLC), naturally present killer lymphoid cell carcinoma in nasal cavity / T-cell lymphoma (testicular tumor), thyroid cancer Malignant melanoma, ovarian tumors, cancer from cysts in the adenoids. Acute stage bone marrow leukemia (AML) Breast cancer lymphocyte leukemia from T-cells in the acute stage of children Cancer of the nervous system Leukemia in mass cells Angioma tissue cancer, abnormal large cell lymphoma Endometrial and prostate cancer
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH83129A TH83129A (en) | 2007-02-22 |
| TH83129B true TH83129B (en) | 2007-02-22 |
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