TH81556B - Antibodies to Interlukin-1 Beta - Google Patents
Antibodies to Interlukin-1 BetaInfo
- Publication number
- TH81556B TH81556B TH601000275A TH0601000275A TH81556B TH 81556 B TH81556 B TH 81556B TH 601000275 A TH601000275 A TH 601000275A TH 0601000275 A TH0601000275 A TH 0601000275A TH 81556 B TH81556 B TH 81556B
- Authority
- TH
- Thailand
- Prior art keywords
- beta
- sequence
- antibodies
- discussed
- interlukin
- Prior art date
Links
- 102000004965 antibodies Human genes 0.000 title claims abstract 4
- 108090001123 antibodies Proteins 0.000 title claims abstract 4
- 102000003777 Interleukin-1 beta Human genes 0.000 claims abstract 4
- 108090000193 Interleukin-1 beta Proteins 0.000 claims abstract 4
- 102000005614 monoclonal antibodies Human genes 0.000 claims abstract 3
- 108010045030 monoclonal antibodies Proteins 0.000 claims abstract 3
- 239000011230 binding agent Substances 0.000 claims 6
- 102000018358 Immunoglobulins Human genes 0.000 abstract 2
- 108060003951 Immunoglobulins Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000038129 antigens Human genes 0.000 abstract 2
- 108091007172 antigens Proteins 0.000 abstract 2
- 229960000070 antineoplastic Monoclonal antibodies Drugs 0.000 abstract 2
- 229960000060 monoclonal antibodies Drugs 0.000 abstract 2
- 210000004408 Hybridomas Anatomy 0.000 abstract 1
- 229940072221 IMMUNOGLOBULINS Drugs 0.000 abstract 1
- 229920001850 Nucleic acid sequence Polymers 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 210000004027 cells Anatomy 0.000 abstract 1
Abstract
แอนติบอดีที่มุ่งต่อแอนติเจน IL-1เบตา และการใช้แอนติบอดีเหล่านี้ได้ถูกกล่าวไว้ โดยเฉพาะโมโนโคลนอลแอนติบอดีมนุษย์สมบูรณ์ที่มุ่งต่อแอนติเจน IL-1เบตา ได้ถูกอภิปรายไว้ ลำดับนิวคลีโอไทด์ซึ่งประมวลรหัส และลำดับกรดอะมิโนซึ่งประกอบรวมด้วยโมเลกุล อิมมูโนโกลบูลินสายหนักและเบา โดยเฉพาะลำดับที่สอดคล้องกับลำดับสายหนักและเบาที่ติดกัน ซึ่งทอดข้ามบริเวณโครงร่าง และ/หรือบริเวณกำหนดความเป็นคู่สม (CDR's) โดยเฉพาะจาก FR1 ถึง FR4 หรือ CDR1 ถึง CDR3 ไฮบริโดมาหรือเซลล์ไลน์อื่น ๆ ซึ่งแสดงโมเลกุลอิมมูโนโกลบูลินและ โมโนโคลนอลแอนติบอดีเหล่านี้ออกมาได้ถูกกล่าวไว้ Antibodies aimed at the IL-1 beta antigen and their use were discussed. In particular, complete human monoclonal antibodies aimed at the IL-1 beta antigen have been discussed. The nucleotide sequence through which the code And the amino acid sequence, which is composed of molecules Heavy and light immunoglobulins In particular, the sequence corresponds to the adjacent heavy and light string sequence. Spanning across the area And / or pairing area (CDR's), especially from FR1 to FR4, or CDR1 to CDR3, hybridoma or other cell lines showing immunoglobulin molecules and These monoclonal antibodies are said to be
Claims (4)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH81556B true TH81556B (en) | 2006-11-30 |
| TH81556A TH81556A (en) | 2006-11-30 |
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