TH80767B - Chemical compound - Google Patents
Chemical compoundInfo
- Publication number
- TH80767B TH80767B TH501006016A TH0501006016A TH80767B TH 80767 B TH80767 B TH 80767B TH 501006016 A TH501006016 A TH 501006016A TH 0501006016 A TH0501006016 A TH 0501006016A TH 80767 B TH80767 B TH 80767B
- Authority
- TH
- Thailand
- Prior art keywords
- ring
- heterocyclic
- formula
- chemical compound
- chemical compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
- KKVYYGGCHJGEFJ-UHFFFAOYSA-N 1-n-(4-chlorophenyl)-6-methyl-5-n-[3-(7h-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine Chemical compound N=1C=CC2=C(NC=3C(=CC=CN=3)C=3C=4N=CNC=4N=CN=3)C(C)=CC=C2C=1NC1=CC=C(Cl)C=C1 KKVYYGGCHJGEFJ-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 101100381978 Mus musculus Braf gene Proteins 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวกับสารประกอบทางเคมี, หรือเกลือของสารเหล่านั้นซึ่งเป็นที่ยอมรับทาง เภสัชศาสตร์ที่มีสูตร (I) (สูตรเคมี) (l) ซึ่งมีความว่องไวในการยับยั้ง B-Raf และดังนั้นจึงเป็นประโยชน์สำหรับความว่องไวในการ ต้านมะเร็งของสารเหล่านั้นและดังนั้นจึงเป็นประโยชน์ในวิธีรักษาร่างกายของคนหรือสัตว์ การ ประดิษฐ์นี้เกี่ยวอีกด้วยกับกรรมวิธีผลิตสารประกอบทางเคมีที่กล่าวแล้ว, สารผสมทางเภสัชศาสตร์ที่ มีสารเหล่านั้นและการใช้สารเหล่านั้นในการผลิตยาสำหรับใช้ในการทำให้เกิดผลในการต้านมะเร็งใน สัตว์เลือดอุ่นเช่น คน: This invention is about chemical compounds, or their salts, which are well established. Pharmacy with formula (I) (chemical formula) (l), which has B-Raf inhibition and is therefore useful for The invention is also related to the production of the aforementioned chemical compounds, pharmaceutical mixtures that There are those substances and their use in the manufacture of drugs for use in inducing anticancer effects in Warm-blooded animals such as people:
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH80767A TH80767A (en) | 2006-10-31 |
| TH80767B true TH80767B (en) | 2006-10-31 |
Family
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