TH79803B - New compound - Google Patents
New compoundInfo
- Publication number
- TH79803B TH79803B TH501005903A TH0501005903A TH79803B TH 79803 B TH79803 B TH 79803B TH 501005903 A TH501005903 A TH 501005903A TH 0501005903 A TH0501005903 A TH 0501005903A TH 79803 B TH79803 B TH 79803B
- Authority
- TH
- Thailand
- Prior art keywords
- new compound
- cyclopropyl
- formula
- compound
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 5
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 3
- NBVXSUQYWXRMNV-UHFFFAOYSA-N Fluoromethane Chemical group FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004429 atoms Chemical group 0.000 claims 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Abstract
การประดิษฐ์นี้จะให้สารประกอบที่มีสูตร (I); (สูตรเคมี) (I) ที่ซึ่ง R1,R2, A, A1 และ B เป็นตามที่ได้กำหนดไว้ในข้อกำหนด; กระบวนการสำหรับการเตรียมของ พวกมัน; สารผสมทางเภสัชกรรมที่มีพวกมันอยู่ด้วย; กระบวนการสำหรับเตรียมสารผสมทาง เภสัชกรรมต่างๆ; และการใช้ของพวกมันในการบำบัด สารประกอบเหล่านี้มีประโยชน์ในการเป็นสาร ยับยั้ง MMP This invention provides a compound with the formula (I); (Chemical formula) (I) where R1, R2, A, A1 and B are as defined in the specification; The process for their preparation; Pharmaceutical mixtures that contain them; Process for the preparation of road mixtures Various pharmaceuticals; And their use in therapy These compounds are useful as MMP inhibitors.
Claims (2)
Publications (2)
Publication Number | Publication Date |
---|---|
TH79803A TH79803A (en) | 2006-09-07 |
TH79803B true TH79803B (en) | 2006-09-07 |
Family
ID=
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