TH79612A - (S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopipe Arazine Hydrochloride Dihydrate - Google Patents
(S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopipe Arazine Hydrochloride DihydrateInfo
- Publication number
- TH79612A TH79612A TH501005571A TH0501005571A TH79612A TH 79612 A TH79612 A TH 79612A TH 501005571 A TH501005571 A TH 501005571A TH 0501005571 A TH0501005571 A TH 0501005571A TH 79612 A TH79612 A TH 79612A
- Authority
- TH
- Thailand
- Prior art keywords
- fluoroisokolin
- sulfonyl
- methyl
- arazine
- homopipe
- Prior art date
Links
- XTURYZYJYQRJDO-BNAHBJSTSA-N (2R)-2-acetamido-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CSC[C@@H](C(O)=O)NC(C)=O XTURYZYJYQRJDO-BNAHBJSTSA-N 0.000 title abstract 3
- NSNHWTBQMQIDCF-UHFFFAOYSA-N dihydrate;hydrochloride Chemical compound O.O.Cl NSNHWTBQMQIDCF-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003814 drug Substances 0.000 claims abstract 3
- 229940079593 drugs Drugs 0.000 claims abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L Calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 229910052925 anhydrite Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000004683 dihydrates Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
Abstract
DC60 (21/02/49) การประดิษฐ์เกี่ยวกับ (S)-(-)-1-(4-ฟลูออโรไอโซควินอลิน-5-อิล)ซัลโฟนิล-2-เมธิล-1,4- ฮอมอพิเพอราซีน ไฮโดรคลอไรด์ ไดไฮเดรท, วิธีผลิตไดไฮเดรท, และเกี่ยวกับสารผสมยาที่มี ไดไฮเดรท สารประกอบของการประดิษฐ์มีสภาพดูดความชื้นน้อยกว่าเมื่อเปรียบเทียบกับผลึก แอนไฮดรัส (S)-(-)-1-(4-ฟลูออโรไอโซควินอลิน-5-อิล)ซัลโฟนิล-2-เมธิล-1,4-ฮอมอพิเพอราซีน ไฮโดรคลอไรด์ และด้วยเหตุนี้จึงแสดงเสถียรภาพทางเคมีที่ดีเยี่ยม การประดิษฐ์เกี่ยวกับ (S)-(-)-1-(4-ฟลูออโรไอโซควินอลิน-5-อิล)ซัลโฟนิล-2-เมธิล-1,4- ฮอมอพิเพอราซีน ไฮโดรคลอไรด์ ไดไฮเดรท, วิธีผลิตไดไฮเดรท, และเกี่ยวกับสารผสมยาที่มี ไดไฮเดรท สารประกอบของการประดิษฐ์มีสภาพดูดความชื้นน้อยกว่าเมื่อเปรียบเทียบกับผลึก แอนไฮดรัส (S)-(-)-1-(4-ฟลูออโรไอโซควินอลิน-5-อิล)ซัลโฟนิล-2-เมธิล-1,4-ฮอมอพิเพอราซีน ไฮโดรคลอไรด์ และด้วยเหตุนี้จึงแสดงเสถียรภาพทางเคมีที่ดีเยี่ยม สิทธิบัตรยา DC60 (21/02/49) Invention about (S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopipe Arazine hydrochloride dihydrate, dihydrate production method, and with regards to dihydrated drug mixtures.The fabrication compound is less hygroscopic compared to anhydrite crystals. Russ (S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopi Perazine hydrochloride and hence exhibits excellent chemical stability. Invention about (S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopipe Arazine hydrochloride dihydrate, dihydrate production method, and with regards to dihydrated drug mixtures.The fabrication compound is less hygroscopic compared to anhydrite crystals. Russ (S) - (-) - 1- (4- fluoroisokolin-5-il) sulfonyl-2-methyl-1,4-homopi Perazine hydrochloride and hence exhibits excellent chemical stability.
Claims (3)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH79612B TH79612B (en) | 2006-08-31 |
| TH79612A true TH79612A (en) | 2006-08-31 |
Family
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