TH79421B - Microfluidized oil-in-water emulsion and vaccine mixtures - Google Patents
Microfluidized oil-in-water emulsion and vaccine mixturesInfo
- Publication number
- TH79421B TH79421B TH501001539A TH0501001539A TH79421B TH 79421 B TH79421 B TH 79421B TH 501001539 A TH501001539 A TH 501001539A TH 0501001539 A TH0501001539 A TH 0501001539A TH 79421 B TH79421 B TH 79421B
- Authority
- TH
- Thailand
- Prior art keywords
- vaccine
- water emulsion
- vaccine mixtures
- mixtures
- emulsion
- Prior art date
Links
- 229960005486 vaccines Drugs 0.000 title claims abstract 7
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 239000007764 o/w emulsion Substances 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 claims abstract 4
- 102000038129 antigens Human genes 0.000 claims abstract 4
- 108091007172 antigens Proteins 0.000 claims abstract 4
- 150000007949 saponins Chemical class 0.000 claims 2
- 235000017709 saponins Nutrition 0.000 claims 2
- 235000003702 sterols Nutrition 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000002338 glycosides Chemical class 0.000 claims 1
- 239000000693 micelle Substances 0.000 claims 1
- 150000003432 sterols Chemical class 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
- 239000000839 emulsion Substances 0.000 abstract 2
- 230000000240 adjuvant Effects 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000002708 enhancing Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้จัดเตรียมอิมัลชันของน้ำมันในน้ำที่มีขนาดซับไมครอนซึ่งใช้ได้ดีดังที่เป็น ตัวยาเสริมวัคซีนสำหรับการเพิ่มฤทธิ์สภาพก่อเกิดภูมิคุ้มกันของแอนติเจน การประดิษฐ์นี้ยัง จัดเตรียมสารผสมของวัคซีนซึ่งมีแอนติเจนซึ่งได้รับการประกอบรวมกับอิมัลชันดังกล่าวแบบภายใน หรือแบบภายนอก วิธีของการเตรียมอิมัลชันและวัคซีนยังได้รับการจัดเตรียมโดยการประดิษฐ์นี้ อีกด้วย This invention provides an oil-in-water emulsion with a micron size that works as well as A vaccine adjuvant for enhancing the immunogenic activity of antigens. This invention also Provide vaccine mixtures containing antigens which have been internally integrated with the emulsion. Or external Methods of emulsion and vaccine are also being prepared by this invention.
Claims (3)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH79421A TH79421A (en) | 2006-08-24 |
| TH79421B true TH79421B (en) | 2006-08-24 |
| TH72570B TH72570B (en) | 2019-11-13 |
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