TH78838B - Benzamide compounds - Google Patents
Benzamide compoundsInfo
- Publication number
- TH78838B TH78838B TH501004143A TH0501004143A TH78838B TH 78838 B TH78838 B TH 78838B TH 501004143 A TH501004143 A TH 501004143A TH 0501004143 A TH0501004143 A TH 0501004143A TH 78838 B TH78838 B TH 78838B
- Authority
- TH
- Thailand
- Prior art keywords
- compounds
- benzamide compounds
- formula
- benzamide
- chemical formula
- Prior art date
Links
- 150000003936 benzamides Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000003282 alkyl amino group Chemical group 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atoms Chemical class [H]* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000001028 anti-proliferant Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drugs Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Abstract
สารประกอบเบนซาไมด์ตามสูตร (I) (สูตรเคมี) I โดยที่ R1a, R1b, R1c, R2, R3, R4, m และ n มีความหมายใด ๆ ดังกำหนดไว้ในคำบรรยาย; กระบวนการในการเตรียมสารประกอบดังกล่าว, สารผสมทางเภสัชกรรมที่มีสารประกอบดังกล่าว และการใช้สารประกอบดังกล่าวในการผลิตยาสำหรับใช้เป็นสารต้านการเพิ่มจำนวนของเซลล์ในการ ป้องกันหรือการรักษาเนื้องอกหรือภาวะอื่นๆ ที่มีการเพิ่มจำนวนของเซลล์ซึ่งไวต่อการยับยั้งฮิสโทน ดีอะซีติเลส (HDAC) Benzamide compounds according to the formula (I) (chemical formula) I, where R1a, R1b, R1c, R2, R3, R4, m and n have any meaning as given in the narration; The process of preparing such compounds, pharmaceutical mixtures containing such compounds And the use of these compounds in the manufacture of drugs for use as an anti-proliferation agent in Prevention or treatment of tumors or other conditions With an increase in the number of cells susceptible to inhibition of histone dacetilase (HDAC)
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH78838A TH78838A (en) | 2006-07-27 |
TH78838B true TH78838B (en) | 2006-07-27 |
Family
ID=
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