TH69663A - Fludara provides an oral formulation of a highly purified formulation with a rapid release of active ingredients. - Google Patents
Fludara provides an oral formulation of a highly purified formulation with a rapid release of active ingredients.Info
- Publication number
- TH69663A TH69663A TH201004766A TH0201004766A TH69663A TH 69663 A TH69663 A TH 69663A TH 201004766 A TH201004766 A TH 201004766A TH 0201004766 A TH0201004766 A TH 0201004766A TH 69663 A TH69663 A TH 69663A
- Authority
- TH
- Thailand
- Prior art keywords
- fludara
- formulation
- provides
- active ingredients
- highly purified
- Prior art date
Links
- GIUYCYHIANZCFB-FJFJXFQQSA-N fludarabine phosphate Chemical compound C1=NC=2C(N)=NC(F)=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O GIUYCYHIANZCFB-FJFJXFQQSA-N 0.000 title claims abstract 7
- 229960005304 fludarabine phosphate Drugs 0.000 title claims abstract 7
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 239000004480 active ingredient Substances 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 239000012535 impurity Substances 0.000 claims abstract 2
- 239000007916 tablet composition Substances 0.000 claims abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 claims 1
- 229960001021 lactose monohydrate Drugs 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims 1
- 239000008108 microcrystalline cellulose Substances 0.000 claims 1
- 229940016286 microcrystalline cellulose Drugs 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
Abstract
DC60 (22/02/55) การประดิษฐ์นี้เกี่ยวข้องกับสูตรผสมยาเม็ดที่มีการปลดปล่อยเร็วที่มีฟลูดารา (fludara) บริสุทธิ์ มากกว่า 99.19% (ฟลูดาราความ บริสุทธิ์สูง) เป็นส่วนผสมออกฤทธิ์ในองค์ประกอบซึ่งได้กำหนด ไว้ สิ่งเจือปนที่เหลืออยู่ การประดิษฐ์นี้เกี่ยวข้องกับ สูตรผสมยาเม็ดกลมแบนการปลอดปล่อยเร็วที่มีฟลูดาราบริสุทธิ์ > 99.19% (ฟลูดาราความ บริสุทธิ์สูง) เป็นส่วนผสมออกฤทธิ์ ในสารผสมซึ่งได้กำหนด ไว้สื่งเจือปนที่ เหลืออยู่ สิทธิบัตรยา DC60 (22/02/55) This invention involves formulation of quick-release tablets containing more than 99.19% pure fludara (high purity fludara) as the active ingredient in the constituents which have been prescribed. Keep the residual impurity This invention involves A fast-release, flat-round tablet formulation containing pure fludara> 99.19% (high purity fludara) as an active ingredient. In the mixture which has been determined To preserve the remaining additives, patent drugs
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH69663A true TH69663A (en) | 2005-07-19 |
Family
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