TH6776A - Tricyclic compound - Google Patents

Abstract

New substances with formulas (Chemical formula) where X is -CH = CH- or S R1 is lower alkyl. Lower alkoxie or trifluoromethyl R2 is hydrogen lower alkyl. Lower alkoxi hydroxy or lower alkanoyloxo R3 and R4 are independent of hydrogen chlorine, fluorine, lower alkyl. Or lower alkoxie R5 is the radical with the formula R6- (CH2) nC = C- or R7-O- (CH2) mC = C- R6 and R7 is an eryil or heterocyclic radical, n is an integer from 0 to 2: t is Integers from 1 to 2 and s are integers from 0 to 1, provided that when s is 1, R2 is hydroxy. Lower Alcoxie Or lower alkanoiloxies, and when n is 0, R6 must be bonded through a bond. Carbon to carbon and R7 are bonded through a carbon-to-carbon bond. Always oxygen and when there is at least one asymmetric center, including enanthiomers and razemates, and the acid salts used. Pharmacy of this substance It exhibits anti-platelet-stimulating factor (PAF) activity, so it is beneficial in disease conditions. Which is characterized by excessive platelet activation factor Or for the prevention and treatment of cardiovascular disease, lung disease, immune disorders Inflammatory disease Skin disorders Shock or refuse Organ change: drug patent

Claims (1)

1. Process for producing formulas (chemical formulas) a) reactions between substances with formulas (chemical formulas) b) interacting substances with formulas (chemical formulas c) for the production of formulas I where s are 1 and R5 are not m Doyty with a basic nitrogen atom Reacts formula I, where s is 0 and R5 is not a moyty with a basic nitrogen atom with peroxi acid (d) for the production of formula I, where s is 0 and R2 is lower alkano. The iloxi reacts a formula I where s is 1 and R2 is hydrogen with lower alkanoids acid anhydrite or e) for tagging: drug patent.