TH57794C3 - The use of chimeric antibody-CD20 antibody as an in vitro or in vitro rinsing agent in patients undergoing BMT or PBSC transplantation. - Google Patents
The use of chimeric antibody-CD20 antibody as an in vitro or in vitro rinsing agent in patients undergoing BMT or PBSC transplantation.Info
- Publication number
- TH57794C3 TH57794C3 TH9901004179A TH9901004179A TH57794C3 TH 57794 C3 TH57794 C3 TH 57794C3 TH 9901004179 A TH9901004179 A TH 9901004179A TH 9901004179 A TH9901004179 A TH 9901004179A TH 57794 C3 TH57794 C3 TH 57794C3
- Authority
- TH
- Thailand
- Prior art keywords
- vitro
- antibody
- cells
- animals
- patients
- Prior art date
Links
- 238000000338 in vitro Methods 0.000 title abstract 6
- 210000002568 pbsc Anatomy 0.000 title 1
- 238000002054 transplantation Methods 0.000 title 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims abstract 5
- 238000011282 treatment Methods 0.000 claims abstract 4
- 241001465754 Metazoa Species 0.000 claims 3
- 241000607479 Yersinia pestis Species 0.000 claims 3
- DIPLXSBTYRDLGV-UHFFFAOYSA-N 2-methyl-2-methylsulfanylpropanal Chemical compound CSC(C)(C)C=O DIPLXSBTYRDLGV-UHFFFAOYSA-N 0.000 claims 2
- QGLZXHRNAYXIBU-WEVVVXLNSA-N aldicarb Chemical compound CNC(=O)O\N=C\C(C)(C)SC QGLZXHRNAYXIBU-WEVVVXLNSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 208000004736 B-Cell Leukemia Diseases 0.000 claims 1
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims 1
- 239000003905 agrochemical Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 230000000361 pesticidal effect Effects 0.000 claims 1
- 239000000575 pesticide Substances 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 238000011363 radioimmunotherapy Methods 0.000 claims 1
- 150000003839 salts Chemical group 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 abstract 2
- 210000001185 bone marrow Anatomy 0.000 abstract 2
- 230000009433 disease-worsening effect Effects 0.000 abstract 2
- 208000032839 leukemia Diseases 0.000 abstract 2
- 210000005259 peripheral blood Anatomy 0.000 abstract 2
- 239000011886 peripheral blood Substances 0.000 abstract 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
Abstract
DC60 (14/10/46) เปิดเผยการใช้ไคเมอริค แอนทิ-CD20 แอนทิบอดี, ริทูซิแมบ เป็นสารชำระล้างในสิ่งมี ชีวิต หรือในหลอดแก้ว, ของผู้ป่วยที่ได้รับการปลูกถ่ายไขกระดูก หรือเพอริเฟอรัล บลัด สเต็มใน ระหว่างการรักษาความร้ายแรงที่เกี่ยวข้องกับ B-เซลล์, ตัวอย่างเช่น B-เซลล์ ลิมโฟมา หรือลูคิเมีย การชำระล้างดังกล่าวอาจเสริมการเอนกราฟท์เมนท์ และ/หรือป้องกันอาการของโรคที่ทรุดลงใน ผู้ป่วยดังกล่าว เปิดเผยการใช้ไคเมอริค แอนที-CD20 แอนทิบอดี, ริทูซิแมบ เป็นสารชำระล้างในสิ่งมี ชีวิต หรือในหลอดแก้ว, ของผู้ป่วยที่ได้รับการปลูกถ่ายไขกระดูก หรือเพอริเฟอรัล บลัด สเต็มใน ระหว่างการรักษาความร้ายแรงที่เกี่ยวข้องกับ B-เซลล์, ตัวอย่างเช่น B-เซลล์ ลิมโฟมา หรือลูคิเมีย การชำระล้างดังกล่าวอาจเสริมการเอนกราฟท์เมนท์ และ/หรือป้องกันอาการของโรคที่ทรุดลงใน ผู้ป่วยดังกล่าว DC60 (14/10/46) revealed the use of chimeric antibody-CD20 antibody, ritusimab as an in vitro or in vitro rinsing agent, in patients receiving Bone marrow transplant Or peripheral blood stem during serious treatment involving B-cells, for example, B-cells, lymphoma, or leukemia. Such cleansing may enhance entrapment. And / or prevent symptoms of disease worsening in Such patients The use of chimeric antibiotic-CD20 antibody, ritusimab as a reagent in vitro or in vitro, in bone marrow transplant patients has been disclosed. Or peripheral blood stem during serious treatment involving B-cells, for example, B-cells, lymphoma, or leukemia. Such cleansing may enhance entrapment. And / or prevent symptoms of disease worsening in Such patients
Claims (4)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH77069A3 TH77069A3 (en) | 2006-04-20 |
| TH57794C3 true TH57794C3 (en) | 2017-09-27 |
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