TH5622A - (2 - ((nitropyridinil) amino) phenyl) aryl methanone in preparation Pirido (1,4) - Benzodiazepin - Google Patents
(2 - ((nitropyridinil) amino) phenyl) aryl methanone in preparation Pirido (1,4) - BenzodiazepinInfo
- Publication number
- TH5622A TH5622A TH8801000282A TH8801000282A TH5622A TH 5622 A TH5622 A TH 5622A TH 8801000282 A TH8801000282 A TH 8801000282A TH 8801000282 A TH8801000282 A TH 8801000282A TH 5622 A TH5622 A TH 5622A
- Authority
- TH
- Thailand
- Prior art keywords
- phenyl
- amino
- molecular weight
- low molecular
- benzodiazepin
- Prior art date
Links
- -1 aryl methanone Chemical compound 0.000 title claims abstract 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title claims 2
- GUJAGMICFDYKNR-UHFFFAOYSA-N 1,4-benzodiazepine Chemical compound N1C=CN=CC2=CC=CC=C12 GUJAGMICFDYKNR-UHFFFAOYSA-N 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract 2
- 230000003993 interaction Effects 0.000 claims 2
- LEVJVKGPFAQPOI-UHFFFAOYSA-N phenylmethanone Chemical compound O=[C]C1=CC=CC=C1 LEVJVKGPFAQPOI-UHFFFAOYSA-N 0.000 claims 2
- MAOBFOXLCJIFLV-UHFFFAOYSA-N (2-aminophenyl)-phenylmethanone Chemical compound NC1=CC=CC=C1C(=O)C1=CC=CC=C1 MAOBFOXLCJIFLV-UHFFFAOYSA-N 0.000 claims 1
- OPACCTXYZFTUOQ-UHFFFAOYSA-N 1h-pyrido[2,3-i][1,4]benzodiazepine Chemical compound N1C=CN=CC2=CC=C(N=CC=C3)C3=C12 OPACCTXYZFTUOQ-UHFFFAOYSA-N 0.000 claims 1
- UUOLETYDNTVQDY-UHFFFAOYSA-N 2-chloro-3-nitropyridine Chemical compound [O-][N+](=O)C1=CC=CN=C1Cl UUOLETYDNTVQDY-UHFFFAOYSA-N 0.000 claims 1
- NYYRRBOMNHUCLB-UHFFFAOYSA-N 3-chloro-n,n-dimethylpropan-1-amine Chemical compound CN(C)CCCCl NYYRRBOMNHUCLB-UHFFFAOYSA-N 0.000 claims 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims 1
- WGYKZJWCGVVSQN-UHFFFAOYSA-N propylamine Chemical compound CCCN WGYKZJWCGVVSQN-UHFFFAOYSA-N 0.000 claims 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Abstract
มีการนำเสนอ(2-( (ไนโตรไพริดินิล) อมิโน) เฟนนิล) อาริลเมทธาโนน ที่มีสูตรดังข้างล่างในฐานะสารตัวกลางทางเคมี และ/หรือ สารที่ออกฤทธิ์ต่อต้านอาการหดหู่ใจ (สูตรเคมี) R1 และ R2 เลือกได้จากกลุ่มที่ประกอบด้วยอัลคิลที่มีน้ำ หนักโมเลกุลต่ำ -C(O)-O- อัลคิลที่มีน้ำหนักโมเลกุลต่ำ หรือ R1 และ R2 ทั้งสองสัญญลักษณ์รวมกันเข้ากับไนโตรเจนที่ อยู่ติดกันแล้วเกิดเป็นส่วนที่เป็นเฮทเทอโรไซคลิคที่เลือก ได้จาก 1-ปิปเปอราซินิล และ1-ปิปเปอราซิน และ 1-ปิปเปอรา ซิน ที่ถูกแทนที่ที่ตำแหน่ง 4 Ar เลือกได้จากกลุ่มที่ปรกอบด้วย 2 หรือ 3 ไธเอนนิล 2,3 หรือ 4-ไพริดินิล,เฟนนิล หรือเฟนนิลที่ถูกแทนที่ด้วยอนุมูล 1 ถึง 3 อนุมูลที่เลือกได้จากฮาโล อัลคิลที่มีน้ำหนัก โมเลกุลต่ำ อัลคอกซีที่มีน้ำหนักโมเลกุลต่ำไตรฟลูออ โรเมทธิล หรือไนโตร โดยที่หมู่แทนที่นั้นอาจเหมือนกันหรือ ต่างกันก็ได้ (2- ((nitropyridyl) amino) phenyl) aryl methanone are presented. Formulated below as a chemical intermediate and / or anti-depressant (chemical formula), R1 and R2 can be selected from the aqueous alkyl group. Low molecular weight-C (O) -O-alkyl low molecular weight, or R1 and R2, both symbolize combined with nitrogen that Adjacent to each other, forming a heterocyclic part that can be selected from 1-Piper Sinil. And 1- pipperacin and 1- pipperacin replaced at position 4 Ar, selectable from groups that include 2 or 3 thienyl 2,3 or 4 - pyridinyl , Fenil Or fennyl replaced with 1 to 3 radicals of choice from halo Low molecular weight alkyl, low molecular weight alkoxy, trifluoromethyl or nitro, where the substitutes may be the same or different.
Claims (2)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH5622A true TH5622A (en) | 1989-02-01 |
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