TH54141A - New compound - Google Patents

Abstract

DC60 This invention deals with compounds with formula (I) and their salts. Which is accepted Pharmaceuticals, which inhibit carboxypeptidase U, and can be used in the prevention and treatment of Related to carboxypeptidase U in other ways, this invention deals with compounds of This invention for therapeutic use; About the process for the preparation of this new compound, about the pharmaceutical constituents that contain this invention. Or the salt of the substance That is, which is a pharmaceutical ingredient, as an active ingredient, at least 1 type; And about using The active compounds for the manufacture of therapeutic agents listed above (chemical formula) (l), this invention deals with compounds g with formula (I) and their salts. Which is accepted Pharmaceuticals, which inhibit carboxypeptidase U, and can be used in the prevention and treatment of diseases related to Related to carboxypeptidase U in other ways, this invention deals with compounds of This invention is for use in the treatment of disease. Regarding the process for the preparation of the new compound, about the pharmaceutical mixtures with this invention compound. Or the salt of that substance, which It is recognized pharmaceutical, as an active ingredient, at least 1 type; And about the use of active ingredients In the manufacture of drugs for the treatment of the above (chemical formulas) (l): drug patents.

Claims (1)

1. Compounds with formula I (chemical formula) (l) or salt of that substance, which are pharmacologically acceptable, where R1 is H, OH, halogen, C1-C6 alkyl, C1-C6 alkyl. Aeryl, C1-C6 alkyl, Cyano, NO2, SH och N (R8) 2 or CO-C1-C6 alkyl, R2 is H, OH, halogen, or C1-C6. Alkyl, R3 is COOR7, SO2R7, S = O = (OR7), P = O (OR7) 2, B (OR7) 2, P = OR7 (OR7), tetrasol or carboxylic. Any acidisolter, R4 is a group of SH, S-CO-C1-C6 alkyl, S-CO-alkyl alkyl or S-CO-aryl, R5 is. Tag: drug patent