TH53148A - 5- eryl-3- (8-azebicclo [3.2.1] oct-3-il) -1,3,4-oxadiazole-2 (3H) -on, Preparation of its derivatives And the use of its derivatives in the treatment of disease - Google Patents
5- eryl-3- (8-azebicclo [3.2.1] oct-3-il) -1,3,4-oxadiazole-2 (3H) -on, Preparation of its derivatives And the use of its derivatives in the treatment of diseaseInfo
- Publication number
- TH53148A TH53148A TH9801001369A TH9801001369A TH53148A TH 53148 A TH53148 A TH 53148A TH 9801001369 A TH9801001369 A TH 9801001369A TH 9801001369 A TH9801001369 A TH 9801001369A TH 53148 A TH53148 A TH 53148A
- Authority
- TH
- Thailand
- Prior art keywords
- hydrogen
- group
- instead
- derivatives
- selecting
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 8
- 239000001257 hydrogen Substances 0.000 claims abstract 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 7
- 125000000217 alkyl group Chemical group 0.000 claims abstract 5
- 125000005843 halogen group Chemical group 0.000 claims abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 4
- 125000003277 amino group Chemical group 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
Abstract
DC60 (17/01/44) สารประกอบของสูตรทั่วไป (I) (สูตรเคมี) (I) ซึ่ง R1 แทนหมู่อัลคิล หรือไซโคลอัลคิลเมทิล, X1 แทนไฮโดรเจนหรือฮาโลเจนอะตอมหรือหมู่อัล คอกซิ หรือโดยที่เลือกได้ OR1 และ X1 รวมกัน แทนหมู่ -OCH2O-, -O(CH2)2-, -O(CH2)3-, -O (CH2)2O- หรือ -O(CH2)3O-, X2 แทนไฮโดรเจน อะตอม หรือหมู่อะมิโน, X3 แทนไฮโดรเจน หรือฮาโลเจน อะตอม และ R2 แทนไฮโดรเจนอะตอม โดยการ เลือกหมู่อัลคิลที่แทนที่, โดยการเลือกหมู่ฟีนิลอัล คิลที่แทนที่หรือ หมู่ -(CH2)nCO-Z ซึ่ง n แทนตัวเลข จาก 1 ถึง 6 และ Z แทนหมู่ 1-พิเพอริดิล การนำไปใช้ในการรักษาโรค สารประกอบของสูตรทั่วไป(1)(สูตรเคมี) (I) ซึ่งR1แทนหมู่อัลคิลหรือไซโคลอัลคิลเมทิล,X1 แทนไฮโดรเจนหรือฮาโลเจนอะตอมหรือหมู่อัล คอกซิหรือโดยที่เลือกได้OR1และ X1รวมกัน แทนหมู่-OCH2O-,-O(CH2)2-,-O(CH2)3,-O (CH2)2O-หรือ-O(CH2)3O-,X2แทนไฮโดรเจน หรือหมู่อะมิโน,X3แทนไฮโดรเจนหรือฮาโลเจน อะตอมและR2แทนไฮโดรเจนอะตอมโดยการ เลือกหมู่อัลคิลที่แทนที่,โดยการเลือกหมู่ฟีนิลอัล คิลที่แทนที่หรือหมู่-(CH2)nCO-Zซึ่งnแทนตัวเลข จาก1ถึง6และZแทนหมู่1-พิเพอริดิล การนำไปใช้ในการรักษาโรค สิทธิบัตรยา DC60 (01/17/44) Compounds of the general formula (I) (Chemical formula) (I), where R1 represents the alkyl group. Or cycloalkylmethyl, X1 instead of hydrogen or halogen atom or alkoxin group, or where optional OR1 and X1 are combined instead of -OCH2O-, -O (CH2) 2-, -O ( CH2) 3-, -O (CH2) 2O- or -O (CH2) 3O-, X2 replaces hydrogen atoms or amino groups, X3 for hydrogen or halogen atoms and R2 for hydrogen atoms by selecting Al group. Replaced kill, by selecting phenyl group The replacement kill or group - (CH2) nCO-Z, where n represents a number from 1 to 6 and Z represents group 1 - piperidil. Compounds of the general formula (1) (chemical formula) (I) in which R1 represents the alkyl group or the cycloalkyl methyl group, X1. Instead of hydrogen or halogen atoms or Al groups Cox or where optional OR1 and X1 are combined instead of -OCH2O -, - O (CH2) 2 -, - O (CH2) 3, -O (CH2) 2O- or -O (CH2) 3O-, X2 instead of hydrogen. Or amino groups, X3 instead of hydrogen or halogen. Atom and R2 represent hydrogen atoms by Select the alkyl group to be replaced, by selecting the phenyl group The replacement kill or squad - (CH2) nCO-Z, where n represents a number. From 1 to 6 and Z represents moo 1-piperidil Applied in the treatment of disease, drug patent
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH53148A true TH53148A (en) | 2002-09-23 |
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