TH43902A3 - DNA vaccines with synergistic agents - Google Patents
DNA vaccines with synergistic agentsInfo
- Publication number
- TH43902A3 TH43902A3 TH9901001079A TH9901001079A TH43902A3 TH 43902 A3 TH43902 A3 TH 43902A3 TH 9901001079 A TH9901001079 A TH 9901001079A TH 9901001079 A TH9901001079 A TH 9901001079A TH 43902 A3 TH43902 A3 TH 43902A3
- Authority
- TH
- Thailand
- Prior art keywords
- virus
- vaccine
- feline
- vaccine according
- dna
- Prior art date
Links
- 239000012747 synergistic agent Substances 0.000 title claims abstract 7
- 229940021995 DNA vaccine Drugs 0.000 title claims abstract 4
- 108010041986 DNA Vaccines Proteins 0.000 title claims abstract 3
- 244000052769 pathogen Species 0.000 claims abstract 6
- 229920001577 copolymer Polymers 0.000 claims abstract 5
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000002773 nucleotide Substances 0.000 claims abstract 4
- 125000003729 nucleotide group Chemical group 0.000 claims abstract 4
- 230000001717 pathogenic effect Effects 0.000 claims abstract 4
- 238000001727 in vivo Methods 0.000 claims abstract 3
- 229920000058 polyacrylate Polymers 0.000 claims abstract 3
- 229920000642 polymer Polymers 0.000 claims abstract 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000005466 alkylenyl group Chemical group 0.000 claims abstract 2
- 230000000890 antigenic effect Effects 0.000 claims abstract 2
- 241000700605 Viruses Species 0.000 claims 18
- 229960005486 vaccine Drugs 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 5
- 241000283690 Bos taurus Species 0.000 claims 4
- 241000282324 Felis Species 0.000 claims 4
- 241000282887 Suidae Species 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 241000271566 Aves Species 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 206010014599 encephalitis Diseases 0.000 claims 3
- 230000002458 infectious effect Effects 0.000 claims 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 206010006451 bronchitis Diseases 0.000 claims 2
- 150000005846 sugar alcohols Chemical class 0.000 claims 2
- 230000002195 synergetic effect Effects 0.000 claims 2
- RFIMISVNSAUMBU-UHFFFAOYSA-N 2-(hydroxymethyl)-2-(prop-2-enoxymethyl)propane-1,3-diol Chemical compound OCC(CO)(CO)COCC=C RFIMISVNSAUMBU-UHFFFAOYSA-N 0.000 claims 1
- 241000589969 Borreliella burgdorferi Species 0.000 claims 1
- 241000711895 Bovine orthopneumovirus Species 0.000 claims 1
- 241000711506 Canine coronavirus Species 0.000 claims 1
- 241000712083 Canine morbillivirus Species 0.000 claims 1
- 241000701931 Canine parvovirus Species 0.000 claims 1
- 241000282465 Canis Species 0.000 claims 1
- 241000282472 Canis lupus familiaris Species 0.000 claims 1
- 206010008631 Cholera Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
- 239000004386 Erythritol Substances 0.000 claims 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 239000005977 Ethylene Substances 0.000 claims 1
- 241000714165 Feline leukemia virus Species 0.000 claims 1
- 241000701915 Feline panleukopenia virus Species 0.000 claims 1
- 241000282326 Felis catus Species 0.000 claims 1
- 241000712003 Human respirovirus 3 Species 0.000 claims 1
- 241001500343 Influenzavirus C Species 0.000 claims 1
- 241000710778 Pestivirus Species 0.000 claims 1
- 241000711902 Pneumovirus Species 0.000 claims 1
- 241000711798 Rabies lyssavirus Species 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- 208000003217 Tetany Diseases 0.000 claims 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
- 229940009714 erythritol Drugs 0.000 claims 1
- 235000019414 erythritol Nutrition 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 244000045947 parasite Species 0.000 claims 1
- 206010034674 peritonitis Diseases 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 229960000834 vinyl ether Drugs 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 2
- 229920002125 Sokalan® Polymers 0.000 abstract 2
- 229960001631 carbomer Drugs 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 abstract 1
- 229940117841 methacrylic acid copolymer Drugs 0.000 abstract 1
Abstract
DC60 (25/06/42) ดีเอนเอวัคซีนประกอบรวมด้วยดีเอนเอเปลือยที่รวมอยู่และแสดงลักษณะในภาวะทดสอบใน กายของลำดับนิวคลีโอไทด์ที่ประมวลรหัสของแอนติเจนิคพอพิเพพไทด์ ที่ควรคือจีนของเชื้อก่อโรค และสารเสริมฤทธิ์อย่างน้อยหนึ่งชนิดที่เลือกจากพอลิเมอร์ของอะคริลิคหรือกรดเมธาคริลิค และโคพอลิ เมอร์ของมาเลอิคแอนไฮไดรด์และอนุพันธ์ของอัลคีนิล สารเสริมฤทธิ์ที่นิยมคือคาร์บอเมอร์หรือ EMA@ ดีเอนเอวัคซีนประกอบรวมด้วยดีเอนเอเปลือยที่รวมอยู่และแสดงลักษณะในภาวะทดสอบในกายของลำดับนิวคลีโอไทด์ที่ประมวลรหัสของแอนติเจนิคพอพิเพพไทด์ที่ควรคือจีนของเชื้อก่อโรคและสารเสริมฤทธิ์อย่างน้อยหนึ่งชนิดที่เลือกจากพอลิเมอร์ของอะคริลิคหรือกรดเมธาคริลิคและโคพอลิเมอร์ของมาเลอิคแอนไฮไดรด์และอนุพันธ์ของอัลคีนิล สารเสริมฤทธิ์ที่นิยมคือคาร์บอเมอร์หรือ EMA@ สิทธิบัตรยา DC60 (25/06/42) DNA Vaccine contains bare DNA included and characterizes the test in The body of the nucleotide sequence that composes the code of the antibiotic popipeptide. That should be the Chinese of the pathogen And at least one synergistic agent selected from acrylic polymer or methacrylic acid copolymer and maleic anhydride copolymer and its derivatives. Kenil A popular synergistic agent is the carbomer, or EMA @ DNA vaccine, contains a bare DNA included and is characterized in the in vivo test condition of the A-coded nucleotide sequence. The supposed antigenic popipeptide is the Chinese of the pathogen and at least one synergistic agent selected from the polymer of acrylic or methacrylic acid. And the maleic anhydride copolymer and its alkylenyl derivatives. Popular synergistic agents are carbomer or EMA @ drug patents.
Claims (9)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH43902A3 true TH43902A3 (en) | 2001-03-26 |
| TH29681C3 TH29681C3 (en) | 2011-03-03 |
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