TH3988B - Devices in a powder dosing device by inhalation - Google Patents

Abstract

The device in the inhalation powder dispenser had been loved before. intended for inhalation and air streams containing pharmacologically active compounds in micron-sized particles. The inhalation powder dispenser consists of an injection unit (2) with a nozzle hole (2a ) and a container unit (3) with a discharge or dosing unit (6) for the active ingredient. The inhalation air stream is at least partially sucked through the air duct (7) located in the container unit (3), extending from the air inlet (8) in contact with the environment. through the aforementioned discharge unit or dose (6) to the injection unit (2) according to this invention. Such deflector devices, in the form of helix cavities(13), etc., are arranged to produce strong deflections for the purpose of dispersing the powder particles. of the inhalable particle size (less than 5 micrometers).

Claims (9)

1. In an inhalation device for inhalation, the air stream produced during inhalation is contained a container of pharmacological compound that is aerosolized or micron-sized. A pipe that extends through a container and has an air inlet, a path for delivering compound sizes to the duct. The outlet pipe for the compound outflow in the supplied air stream through at least some of the air inlet. And a nozzle with one nozzle hole and connected to the outlet of the pipe The hose and the nozzles together form a channel for the compound to be released after inhalation. The enhancement consists of a deflector pathway to provide a strong deflection and accelerate the movement of air currents and compounds through the channel relative to the channel axis. In which the deflector path is fixed within at least one of the linear channels between the compound size transmission path and the nozzle hole. The deflection path, at least, has a sufficiently large radial boundary toward the axis of the channel, such that the radial boundary of any open space along the axial axis of the cavity adjacent to the deflection path is comparatively small. With the radial boundary of the deflection trajectory Hence, the deflector path promotes dispersion of the drug powder groups into particles within the range to be inhaled by causing the collision of the group to the deflector path or against each other. 2. Improvement according to claim 1, where the deflector path consists of a deflector component that is shaped and positioned to divert the air current and the rotational compound relative to the axis of the cavity. 3. Improvement according to claim 2, where there is an axial clearance of the channel adjacent to the deflector path to reduce the resistance of air currents and compounds. 4. Adjustment according to claim 3, in which the ratio of the radial boundary of the open to the radial boundary of the deflection trajectory is not more than one to two. 5. Enhancement to claim 2, in which the deflection path is shaped to be at least one helix-shaped segment along the aforementioned line of the channel. 6. Improvement according to claim 5, which is in the nozzle adjacent to the nozzle hole. 7. Adjustment according to claim 6, in which part of the nozzle directing the upper current from that episode in relation to the air flow direction and the compound passing through it has a steadily reduced cross-sectional area. To increase air flow and compound velocity 8. Improvement according to claim 5, where the episode is in a straight pipe between the dose discharge route and the outlet of the pipe. 9. Improvement according to claim 5, where the cross-sectional area of the helix is between 5 square millimeters and 50 square millimeters, and the length of the section is between 5mm and 50mm 1 0. Modification according to claim 4, which has at least one air inlet to the channel between the dose release route and the nozzle to spray diluted air into the air stream and the compound.