TH31340A - New derivatives of amino acids. And the use of such substances will inhibit thrombin. - Google Patents
New derivatives of amino acids. And the use of such substances will inhibit thrombin.Info
- Publication number
- TH31340A TH31340A TH9701002196A TH9701002196A TH31340A TH 31340 A TH31340 A TH 31340A TH 9701002196 A TH9701002196 A TH 9701002196A TH 9701002196 A TH9701002196 A TH 9701002196A TH 31340 A TH31340 A TH 31340A
- Authority
- TH
- Thailand
- Prior art keywords
- formula
- substances
- amino acids
- new derivatives
- inhibit thrombin
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 6
- 108090000190 Thrombin Proteins 0.000 title claims abstract 5
- 229960004072 thrombin Drugs 0.000 title claims abstract 5
- 150000001413 amino acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 5
- 108090000790 Enzymes Proteins 0.000 claims abstract 2
- 102000004190 Enzymes Human genes 0.000 claims abstract 2
- 208000007536 Thrombosis Diseases 0.000 claims abstract 2
- 230000001455 anti-clotting effect Effects 0.000 claims abstract 2
- 229940088598 enzyme Drugs 0.000 claims abstract 2
- 230000005764 inhibitory process Effects 0.000 claims abstract 2
Abstract
DC60 (29/07/40) การประดิษฐ์นี้ ได้จัดให้มีไว้ด้วย สารประกอบของสูตร I (สูตรเคมี) I โดยที่ R1, R2, R3 ,RX, Y, n และ B ที่มีความหมายตามที่ได้ให้ไว้ในรายละเอียดของการ ประดิษฐ์ ที่นำมาใช้ประโยชน์ในการเป็นตัวยับยั้งคู่แข่งของเอนไซม์ย่อยโปรตีน ที่ทริป สิน เช่น ธรอมบิน และโดยเฉพาะในการบำบัดสภาวะที่ต้องการการยับยั้งธรอมบิน (เช่นการเกิดลิ่มเลือด) หรือการต่อต้านการเกิดการรวมกันเป็นก้อนของเลือด การประดิษฐ์นี้ได้จัดให้มีไว้ด้วย สารประกอบของสูตร I (สูตรเคมี) DC60 (29/07/40) invention of this Has provided Compounds of Formula I (chemical formula) I, where R1, R2, R3, RX, Y, n and B are defined as described in the description of the utilized invention as a competitor of Tripin-digestive enzymes, such as thrombin, and especially in the treatment of conditions requiring thrombin inhibition (Eg thrombosis) or anti-clotting This invention has also provided Compounds of formula I (chemical formula)
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH31340A true TH31340A (en) | 1998-12-15 |
Family
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