TH28832B - Substituted benzyl amino piperidin - Google Patents

Abstract

This invention provides the compound formulation (chemical formula) (I) and various salts that are well established in its pharmaceutical field, where R is C1-C8 alkyl halo, C2-C8 alkylenyl halo. , C2-C8 alkyl or halo C1-C8 alkyl replaced by hydroxy or C1-C8 alkyl, R1 alkoxy hydrogen, halo or C1-C6 alkoxy. ; Or R and R1, together with the two carbon atoms between the benzene ring and R and R1, form C4-C6, a completely connected cycloalkyl. With oxygen replacing any carbon atom And with one or two carbon atoms being replaced by a representative chosen from halo, C1-C6 alkyl and up to five C1-C6 alkyl halo, X is C1-C8. Lycoxi, halo C1-C6 alkyl, phoxi or halo Ar are phenyls that have been replaced by halo. These compounds are useful in the treatment of Disorders of the digestive system System malfunction Central nervous disorders, inflammation, vomiting, incontinence, pain, migraine pain, sunburn, vascular growth, disease, disorders and resistance conditions caused by Helicobacter pytori (Helicobacter pytori) or similar. Especially Central nervous system disorders in mammals Especially humans:

Claims (1)

1. Compounds Formula (I) (Chemical Formula) (I) and its pharmacologically acceptable salts, where R is halo C2-C8 Alkenyl, Halocycline Alkenyl up to C8. Halo C2-C8 Alkenyl or Halocyclic Alkenyl up to C8 R1 is hydrogen, halo or C1-C6 alkoxy, or R and R1, together with two carbon atoms between The ring on the scene with R and R1 forms the C4-C6, a fully bonded cycloalkyl. With oxygen