TH22190B - Composition of skin care agents containing amides And retinol or retinil ester - Google Patents
Composition of skin care agents containing amides And retinol or retinil esterInfo
- Publication number
- TH22190B TH22190B TH9701003903A TH9701003903A TH22190B TH 22190 B TH22190 B TH 22190B TH 9701003903 A TH9701003903 A TH 9701003903A TH 9701003903 A TH9701003903 A TH 9701003903A TH 22190 B TH22190 B TH 22190B
- Authority
- TH
- Thailand
- Prior art keywords
- retinol
- ester
- skin
- retinil
- approximately
- Prior art date
Links
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 title claims abstract 12
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 title claims abstract 6
- 229960003471 retinol Drugs 0.000 title claims abstract 6
- 235000020944 retinol Nutrition 0.000 title claims abstract 6
- 239000011607 retinol Substances 0.000 title claims abstract 6
- 150000001408 amides Chemical class 0.000 title claims abstract 4
- 239000000203 mixture Substances 0.000 title claims 3
- 150000002148 esters Chemical class 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract 5
- 229930195729 fatty acid Natural products 0.000 claims abstract 5
- 239000000194 fatty acid Substances 0.000 claims abstract 5
- 150000004665 fatty acids Chemical class 0.000 claims abstract 5
- 239000000126 substance Substances 0.000 claims 2
- 206010013786 Dry skin Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 230000037336 dry skin Effects 0.000 claims 1
- 210000002374 sebum Anatomy 0.000 claims 1
- 230000037303 wrinkles Effects 0.000 claims 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 4
- 229930002330 retinoic acid Natural products 0.000 abstract 4
- 229960001727 tretinoin Drugs 0.000 abstract 4
- 102100027841 Acyl-CoA wax alcohol acyltransferase 2 Human genes 0.000 abstract 2
- 102100033356 Lecithin retinol acyltransferase Human genes 0.000 abstract 2
- DOEADYYICZVJDD-UHFFFAOYSA-N [4-[(4-aminophenyl)diazenyl]phenyl]arsonic acid Chemical compound C1=CC(N)=CC=C1N=NC1=CC=C([As](O)(O)=O)C=C1 DOEADYYICZVJDD-UHFFFAOYSA-N 0.000 abstract 2
- 108010024239 aromatic amino acid aminotransferase Proteins 0.000 abstract 2
- 230000032050 esterification Effects 0.000 abstract 2
- 238000005886 esterification reaction Methods 0.000 abstract 2
- -1 inactivated retinol ester Chemical class 0.000 abstract 2
- 108010084957 lecithin-retinol acyltransferase Proteins 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
Abstract
DC60 (22/12/40) เอไมด์ ของกรดไขมันที่มีหมู่แทนที่ที่-N ของโครงสร้างโดยเฉพาะที่ยับยั้ง LRAT หรือ ARAT อย่างพอเพียงที่จะเร่งปฏิกิริยาเอสเตอริฟิเคชันของเรตินอลให้เป็นเรตินิลเอสเตอร์ที่ไม่ออก ฤทธิ์ ดังนั้นจะมีผลต่อเคอราติโนไซท์ที่เหมือนกับกรดเรติโนอิก ผลของเรตินอลหรือเรตินิล เอสเตอร์ รวมกับเอไมด์ของกรดไขมันที่มีหมู่แทนที่ที่-N ที่คล้ายกับการรักษาด้วยกรดเรติโนอิก เอไมด์ ของกรดไขมันที่มีหมู่แทนที่ที่-N ของโครงสร้างโดยเฉพาะที่ยับยั้ง LRAT หรือ ARAT อย่างพอเพียงที่จะเร่งปฏิกิริยาเอสเตอริฟิเคชันของเรตินอลให้เป็นเรตินิลเอสเตอร์ที่ไม่ออก ฤทธิ์ ดังนั้นจะมีผลต่อเคอราติโนไซท์ที่เหมือนกับกรดเรติโนอิก ผลของเรตินอลหรือเรตินิล เอสเตอร์ รวมกับเอไมด์ของกรดไขมันที่มีหมู่แทนที่ที่-N ที่คล้ายกับการรักษาด้วยกรดเรติโนอิก DC60 (22/12/40) fatty acid amide with the -N substitution group. Of particular structures that sufficiently inhibit LRAT or ARAT to catalyze retinol esterification to inactivated retinol ester, thus affecting curatinoside. This is the same as retinoic acid. Effect of retinol or retinil ester combined with amide of fatty acid with the -N group. Similar to treatment with retinoic acid amide of fatty acids with the -N substitution group. Of particular structures that sufficiently inhibit LRAT or ARAT to catalyze retinol esterification to inactivated retinol ester, thus affecting curatinoside. This is the same as retinoic acid. Effect of retinol or retinil ester combined with amide of fatty acid with the -N group. That is similar to treatment with retinoic acid
Claims (2)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH29032A TH29032A (en) | 1998-06-25 |
| TH22190B true TH22190B (en) | 2007-07-23 |
Family
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