TH170519A - Genetically modified second-type bonomorphogenetic protein. - Google Patents
Genetically modified second-type bonomorphogenetic protein.Info
- Publication number
- TH170519A TH170519A TH1601005894A TH1601005894A TH170519A TH 170519 A TH170519 A TH 170519A TH 1601005894 A TH1601005894 A TH 1601005894A TH 1601005894 A TH1601005894 A TH 1601005894A TH 170519 A TH170519 A TH 170519A
- Authority
- TH
- Thailand
- Prior art keywords
- protein
- amino acid
- acid sequence
- seq
- type
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title claims abstract 7
- 108090000623 proteins and genes Proteins 0.000 title claims abstract 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract 8
- 230000004927 fusion Effects 0.000 claims abstract 7
- 125000003277 amino group Chemical group 0.000 claims abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract 4
- 230000014509 gene expression Effects 0.000 claims abstract 2
- 229920002704 polyhistidine Polymers 0.000 claims abstract 2
- 230000001413 cellular Effects 0.000 claims 1
- 230000001131 transforming Effects 0.000 claims 1
- 102100005377 BMP2 Human genes 0.000 abstract 1
- 101700000123 BMP2 Proteins 0.000 abstract 1
Abstract
การเปิดเผยนี้รวมถึงเปปไทด์ฟิวชัน เปปไทด์ฟิวชันโดยทั่วไปประกอบรวมด้วยโปรตีนโบนมอร์โฟเจ เนติกชนิดที่สอง (BMP-2) ซึ่งมีปลายสายโซ่ด้านที่มีหมู่เอมีนอิสระผสมกับลำดับกรดอะมิโนดังนี้ กำหนดใน SEQ ID No. 1 รูปแบบหนึ่งของเปปไทด์ฟิวชันที่มีการแสดงออกสามารถถูกแสดงด้วย ลำดับกรดอะมิโนดังแสดงเป็น SEQ ID No. 2 ที่มีพอลิฮีสทิดีนติดกับปลายสายโซ่ด้านที่มีหมู่เอมีน อิสระพร้อมกับส่วนโปรตีนสแตเทอรินดังแสดงใน SEQ ID No. 1 ลำดับกรดอะมิโนที่ผสมจะช่วยใน การเปลี่ยนสภาพของเซลล์ ตัวอย่างหนึ่งคือการสะสมของโปรตีนโบนมอร์โฟเจเนติกชนิดที่สอง บน โครงสร้างที่มีลักษณะคล้ายกระดูก This revelation includes fusion peptides. Fusion peptides generally contain the protein bonomorphge. The second type of netic (BMP-2), which has a side chain end with a free amine group mixed with the following amino acid sequence, is defined in SEQ ID No. 1, a form of fusion peptide at There are expressions can also be expressed. The amino acid sequence is shown as SEQ ID No. 2 with polyhistidine attached to the end of the amine group. The amino acid sequence, along with the protein-steroid fraction, is shown in SEQ ID No. 1. Cell replacement One example is the deposition of a second type of bonomorphogenetic protein on a bone-like structure.
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH170519A true TH170519A (en) | 2017-11-16 |
TH170519B TH170519B (en) | 2017-11-16 |
Family
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