TH170263A - Amino-cyclobutane derivatives, method for the preparation of such And their use - Google Patents

Abstract

New application updated on 20/04/2016 The present invention relates to derivatives of aminocyclobutane, in particular, as NMDA receptor antagonists, their use in human therapeutics, and methods of preparing them. These compounds shall comply with the general formula (1): (chemical formula) (1) where: - X1 represents a hydrogen atom or a fluorine atom; - X2 represents a hydrogen atom or a fluorine atom or a chlorine atom; - R1 represents a hydrogen atom or a fluorine atom or a chlorine atom or a methyl group or a methoxy group or a cyano group; - R2 represents, independently or in combination, a methyl group or an ethyl group.

Claims (2)

: New request, updated 20/04/2016, this invention relates to amino-cyclobutane derivatives. (aminocyclobutane), specifically NMDA receptor antagonists (NMDA receptor antagonists), their use in human therapy. And the methods of preparing them These compounds correspond to the general formula (1): (chemical formula) (1) where: - X1 is a hydrogen atom. Or fluorine atoms; - X2 is a hydrogen atom. Or fluorine atoms Or chlorine atoms; R1 represents hydrogen atom. Or fluorine atoms Or chlorine atoms Or methyl group or methoxy group or Cyano group; - R2 represent independently of each other. Or by joining the methyl group or the ethyl group (Item one) which will appear on the advertisement page: new request, update 20/04/2016 1. Compounds according to the general formula (1): (chemical formula) (1) or their salts or solvates acceptable in pharmaceuticals, where: - X1 represents hydrogen atoms. Or fluorine atoms; - X2 is a hydrogen atom. Or fluorine atoms Or cholrene atom; R1 represents hydrogen atom. Or fluorine atoms Or chlorine atoms Or methyl group or methoxy group or Cyano group; - R2 represent independently of each other. Or by joining the methyl group or the ethyl group 2. Compound according to claim 1, tagged: drug patent