TH170181A - New useful methyl-piperidine compound to inhibit microsomal Prostaglandin E2 Synthes-1 - Google Patents
New useful methyl-piperidine compound to inhibit microsomal Prostaglandin E2 Synthes-1Info
- Publication number
- TH170181A TH170181A TH1701002341A TH1701002341A TH170181A TH 170181 A TH170181 A TH 170181A TH 1701002341 A TH1701002341 A TH 1701002341A TH 1701002341 A TH1701002341 A TH 1701002341A TH 170181 A TH170181 A TH 170181A
- Authority
- TH
- Thailand
- Prior art keywords
- chemical formula
- synthes
- formula
- compound
- piperidine compound
- Prior art date
Links
- XEYBRNLFEZDVAW-ARSRFYASSA-N (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 title 1
- 229960002986 dinoprostone Drugs 0.000 title 1
- -1 methyl-piperidine compound Chemical class 0.000 title 1
- 230000003228 microsomal Effects 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 13
- 150000001875 compounds Chemical class 0.000 claims abstract 9
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 239000011780 sodium chloride Substances 0.000 claims abstract 4
- 206010003246 Arthritis Diseases 0.000 claims abstract 3
- 206010061218 Inflammation Diseases 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 230000004054 inflammatory process Effects 0.000 claims abstract 2
- 208000009883 Joint Disease Diseases 0.000 claims 1
Abstract
การประดิษฐ์นี้ให้สารประกอบของสูตร 1, หรือเกลือของสารนั้นที่ยอมรับกันทางเภสัชกรรม, (สูตรเคมี) 1, ที่ซึ่ง R, R1 และ G คือตามที่บรรยายในที่นี้; วิธีเตรียมสารประกอบ; และการใช้สารประกอบ เพื่อรักษาอาการปวด และ/หรือการอักเสบที่เกี่ยวข้องกับข้ออักเสบ หรือโรคข้อกระดูกอักเสบ สิทธิบัตรยา This invention gives a compound of Formula 1, or a salt of that substance, which is pharmacologically acceptable, (chemical formula) 1, where R, R1 and G are described here; How to prepare the compound; And use of compounds To treat pain And / or inflammation associated with arthritis Or drug patent arthritis
Claims (3)
Publications (2)
Publication Number | Publication Date |
---|---|
TH170181A true TH170181A (en) | 2017-11-02 |
TH170181B TH170181B (en) | 2017-11-02 |
Family
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