TH169612A - Piperidinyl Tetrahydroquinoline has been replaced. And their use as alpha-2c adrenoreceptor antagonist. - Google Patents

Abstract

EDIT 13/09/2016 This invention involves new substituted piperidinyltetrahydroquinolines, involving a process for their preparation, involving Their use is for therapy and / or prophylaxis and involves their use for the preparation of pharmaceuticals, therapeutic drugs and / or Prophylaxis, especially for therapy and / or prevention Small vascular disease Cause of diabetes, canker sores on the limbs caused by diabetes, especially for promoting healing Wounds of diabetic foot ulcers, diabetic heart failure, heart disorders. About small coronary arteries for diabetes mellitus, peripheral and cardiovascular abnormalities, thrombocytopenia and local ischemia, hemodynamic disruption. Peripheral, Raynoid syndrome, Crest syndrome (CREST), vascular obstruction, intermittent leg pain Ischemia, and peripheral and autonomic neuropathy ----------------------------------------------- Invention times This is related to the new substituted piperidinyltetrahydroquinolines, with respect to the process for their preparation, with their use for therapy. And / or disease prevention And relates to their use for the preparation of pharmaceuticals, drugs for therapy and / or Prophylaxis, especially for therapy and / or prevention Small selection tube disease Cause of diabetes, canker sores on the limbs caused by diabetes, especially for promoting healing Wounds of diabetic foot ulcers, diabetic heart failure, heart disorders. About pseudo-micro-coronary artery disease, diabetes mellitus, peripheral vascular disorders, and of the heart, thrombocytopenia and local ischemia, vascular disruption of Periphery, raynoid syndrome, Crest syndrome (CREST), peripheral vascular obstruction, intermittent leg pain. Ischemia, and peripheral neuropathy and autoimmune drug patents.

Claims (1)

: EDIT 13/09/2016 This invention involves new substituted piperidinyltetrahydroquinolines, involving a process for their preparation, involving Their use is for therapy and / or prophylaxis and involves their use for the preparation of pharmaceuticals, therapeutic drugs and / or Prophylaxis, especially for therapy and / or prevention Small vascular disease Cause of diabetes, canker sores on the limbs caused by diabetes, especially for promoting healing Wounds of diabetic foot ulcers, diabetic heart failure, heart disorders. About small coronary arteries for diabetes mellitus, peripheral and cardiovascular abnormalities, thrombocytopenia and local ischemia, hemodynamic disruption. Peripheral, Raynoid syndrome, Crest syndrome (CREST), vascular obstruction, intermittent leg pain Ischemia, and peripheral and autonomic neuropathy ----------------------------------------------- Invention times This is related to new substituted piperidinyltetrahydroquinolines, with respect to the process for their preparation, involving their use for therapy. And / or disease prevention And relates to their use for the preparation of pharmaceuticals, drugs for therapy and / or Prophylaxis, especially for therapy and / or prevention Small selection tube disease Causes of diabetes, canker sores on the limbs caused by diabetes, especially for promoting healing Diabetic foot ulcers, diabetic heart failure, heart disorders About pseudo-small coronary blood disease, diabetes mellitus, peripheral vascular disorders, and of the heart, thrombocytopenia and local ischemia, vascular disruption of Periphery, raynoid syndrome, Crest syndrome (CREST), peripheral vascular obstruction, intermittent leg pain. Ischemia, and peripheral neuropathy and autonomic arthritis (Item one) which will appear on the advertisement page: edit 13/09/2016 1. Compounds according to the formula (I) (chemical formula) (I) where R1 represents C1-C6-alkyl or C3-C5-cycloalkyl, where the alkyl is replaced by 1. Up to 2 agents who are chosen independently of each other From group containing hydroxy, C1-C4-alkoxy and halotag: drug patent