TH169359A - Dual selective inhibitors of P13, delta kinase and gamma (DUAL SELECTIVE PI3 DELTA AND GAMMA KINASE INHIBITORS). - Google Patents
Dual selective inhibitors of P13, delta kinase and gamma (DUAL SELECTIVE PI3 DELTA AND GAMMA KINASE INHIBITORS).Info
- Publication number
- TH169359A TH169359A TH1501007301A TH1501007301A TH169359A TH 169359 A TH169359 A TH 169359A TH 1501007301 A TH1501007301 A TH 1501007301A TH 1501007301 A TH1501007301 A TH 1501007301A TH 169359 A TH169359 A TH 169359A
- Authority
- TH
- Thailand
- Prior art keywords
- gamma
- delta
- kinase
- inhibitors
- dual selective
- Prior art date
Links
- 102000030951 Phosphotransferases Human genes 0.000 title 1
- 108091000081 Phosphotransferases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 1
- 102000010400 1-phosphatidylinositol-3-kinase activity proteins Human genes 0.000 claims abstract 4
- 108040005185 1-phosphatidylinositol-3-kinase activity proteins Proteins 0.000 claims abstract 4
- 201000010099 disease Diseases 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 4
- 102000001253 Protein Kinases Human genes 0.000 claims abstract 2
- 108060006633 Protein Kinases Proteins 0.000 claims abstract 2
- 230000002265 prevention Effects 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims 4
- 125000004180 3-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(F)=C1[H] 0.000 claims 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 239000000470 constituent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 238000005067 remediation Methods 0.000 claims 1
- 230000000051 modifying Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับตัวควบคุมปรับสภาพชนิดคู่ของเดลต้า (สูตร) และแกมม่า (สูตร) โปรตีน ไคเนส PI3K, วิธีการในการเตรียมสารเหล่านั้น, องค์ประกอบทางเภสัชกรรมที่มีสารเหล่านั้นและ วิธีการในการบำบัด, การป้องกันและ/หรือการเยียวยาโรคหรือความผิดปกติที่เกิดจาก PI3K ไคเนสด้วย สารเหล่านั้น สิทธิบัตรยา The invention involved a delta-pair modulation regulator (formula) and gamma (formula) PI3K protein kinase, a method for the preparation of those substances, a pharmaceutical composition containing those substances, and Methods for treating, prevention and / or remedies for diseases or disorders caused by PI3K kinase with those substances.
Claims (3)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH169359A true TH169359A (en) | 2017-10-19 |
| TH1501007301A TH1501007301A (en) | 2017-10-19 |
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