TH168957B - A useful substituted quinoline derivative as an HIV inhibitor, integrative. - Google Patents
A useful substituted quinoline derivative as an HIV inhibitor, integrative.Info
- Publication number
- TH168957B TH168957B TH1601001727A TH1601001727A TH168957B TH 168957 B TH168957 B TH 168957B TH 1601001727 A TH1601001727 A TH 1601001727A TH 1601001727 A TH1601001727 A TH 1601001727A TH 168957 B TH168957 B TH 168957B
- Authority
- TH
- Thailand
- Prior art keywords
- integrative
- quinoline derivative
- substituted quinoline
- hiv inhibitor
- useful substituted
- Prior art date
Links
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 239000003814 drug Substances 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 239000011780 sodium chloride Substances 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000002619 bicyclic group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 125000002471 4H-quinolizinyl group Chemical class C=1(C=CCN2C=CC=CC12)* 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrugs Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Abstract
การประดิษฐ์ครั้งนี้เกี่ยวข้องกับอนุพันธ์ควิโนลิซีนที่ถูกแทนที่ (Substituted Quinolizine Derivatives) ตามสูตร (สูตรเคมี) (I) และเกลือหรือโปร-ดรักของพวกมันที่ยอมรับได้ในทางเภสัชกรรม, โดยที่ X, Y, R1, R2, R3, R4, R5, R9 และ R10 คือดังที่ถูกนิยามไว้ในที่นี้ อีกทั้งการประดิษฐ์ครั้งนี้จะเกี่ยวข้องกับองค์ประกอบซึ่งประกอบ รวมด้วยอย่างน้อยหนึ่งอย่างของอนุพันธ์ควิโนลิซีนที่ถูกแทนที่, และวิธีการของการใช้งานอนุพันธ์ ควิโนลิซีนที่ถูกแทนที่สำหรับการบำบัดหรือการป้องกันการติดเชื้อ HIV ในเป้าหมาย The invention involved Substituted Quinolizine Derivatives according to the formula (Chemical formula) (I) and their salts or pro-drugs that are acceptable in medicine, where X, Y. , R1, R2, R3, R4, R5, R9 and R10 are, as defined here. Moreover, this invention is related to the elements that comprise Include at least one of the substituted quinolysine derivatives, and methods of their use. Substituted quinolizine for targeted HIV therapy or prevention
Claims (1)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH168957B true TH168957B (en) | 2017-10-12 |
| TH168957A TH168957A (en) | 2017-10-12 |
| TH1601001727A TH1601001727A (en) | 2017-10-12 |
Family
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