TH166468A - Pharmaceutical form containing sodium. 1- (6- (morpholin-4-il) pyrimidin-4-il) -4- (1H-1,2,3-triazole-1-il) -1H -Pyrazol-5-olet - Google Patents
Pharmaceutical form containing sodium. 1- (6- (morpholin-4-il) pyrimidin-4-il) -4- (1H-1,2,3-triazole-1-il) -1H -Pyrazol-5-oletInfo
- Publication number
- TH166468A TH166468A TH1601002081A TH1601002081A TH166468A TH 166468 A TH166468 A TH 166468A TH 1601002081 A TH1601002081 A TH 1601002081A TH 1601002081 A TH1601002081 A TH 1601002081A TH 166468 A TH166468 A TH 166468A
- Authority
- TH
- Thailand
- Prior art keywords
- morpholin
- pyrazol
- pyrimidin
- triazole
- containing sodium
- Prior art date
Links
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 title claims abstract 3
- 229910052708 sodium Inorganic materials 0.000 title claims abstract 3
- 239000011734 sodium Substances 0.000 title claims abstract 3
- 239000004480 active ingredient Substances 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 3
- 229940079593 drugs Drugs 0.000 claims abstract 3
- 239000007787 solid Substances 0.000 claims abstract 2
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 abstract 2
- 208000007502 Anemia Diseases 0.000 abstract 1
- 206010007554 Cardiac failure Diseases 0.000 abstract 1
- 208000008787 Cardiovascular Disease Diseases 0.000 abstract 1
- 206010019280 Heart failure Diseases 0.000 abstract 1
- 210000003734 Kidney Anatomy 0.000 abstract 1
- 206010062237 Renal impairment Diseases 0.000 abstract 1
- 230000001684 chronic Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับรูปแบบเภสัขภัณฑ์ที่เป็นของแข็งสำหรับให้ทางปาก ซึ่งประกอบ รวมด้วยโซเดียม 1-[6-(มอร์โฟลิน-4-อิล)ไพริมิดิน-4-อิล]-4-(1H-1,2,3-ไตรอะโซล-1-อิล)-1H- ไพราโซล-5-โอเลต (สารออกฤทธิ์ (I)) ซึ่งมีลักษณะเฉพาะโดยที่มีการปลดปล่อยสารออกฤทธิ์ (I) และ ยังเกี่ยวข้องกับวิธีการเตรียมรูปแบบเภสัชภัณฑ์ดังกล่าว, การใช้รูปแบบเภสัชภัณฑ์ดังกล่าวในฐานะ ตัวยา และการใช้รูปแบบเภสัชภัณฑ์ดังกล่าวสำหรับการป้องกัน, การป้องกันทุติยภูมิ หรือการรักษา ความผิดปกติ โดยเฉพาะความผิดปกติของหัวใจและหลอดเลือด, ภาวะหัวใจวาย, ภาวะเลือดจาง, ความผิดปกติเรื้อรังของไต และภาวะไตเสื่อมสมรรถภาพ สิทธิบัตรยา The invention involved a solid oral form containing sodium. 1- (6- (morpholin-4-il) pyrimidin-4-il) -4- (1H-1,2,3-triazole-1-il) -1H - pyrazol-5-olate (active ingredient (I)), which is characterized by the release of active ingredient (I) and is also related to the method of preparing such pharmaceutical forms, the use of pharmaceutical forms. As a drug and its pharmaceutical form use for the prevention, secondary prevention or treatment of disorders, especially cardiovascular disorders, heart failure, anemia, dysfunction. Chronic kidney And renal impairment, drug patents
Claims (1)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH166468B TH166468B (en) | 2017-08-24 |
| TH166468A true TH166468A (en) | 2017-08-24 |
| TH1601002081A TH1601002081A (en) | 2017-08-24 |
Family
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| TH166468B (en) | Pharmaceutical form containing sodium. 1- (6- (morpholin-4-il) pyrimidin-4-il) -4- (1H-1,2,3-triazole-1-il) -1H - pyrazol-5-olet |