TH163150A - Dosage form of progesterone receptor anesthesia - Google Patents
Dosage form of progesterone receptor anesthesiaInfo
- Publication number
- TH163150A TH163150A TH1501006213A TH1501006213A TH163150A TH 163150 A TH163150 A TH 163150A TH 1501006213 A TH1501006213 A TH 1501006213A TH 1501006213 A TH1501006213 A TH 1501006213A TH 163150 A TH163150 A TH 163150A
- Authority
- TH
- Thailand
- Prior art keywords
- dosage form
- formula
- anesthesia
- uterine
- progesterone receptor
- Prior art date
Links
- 206010002091 Anaesthesia Diseases 0.000 title 1
- 230000037005 anaesthesia Effects 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
- 102000003998 progesterone receptors Human genes 0.000 title 1
- 108090000468 progesterone receptors Proteins 0.000 title 1
- 239000005426 pharmaceutical component Substances 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 2
- XUCNUKMRBVNAPB-UHFFFAOYSA-N Vinyl fluoride Chemical group FC=C XUCNUKMRBVNAPB-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 125000006340 pentafluoro ethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 210000004696 Endometrium Anatomy 0.000 abstract 1
- 208000007106 Menorrhagia Diseases 0.000 abstract 1
- 241001529870 Meoma Species 0.000 abstract 1
- RJKFOVLPORLFTN-STHVQZNPSA-N Progesterone Natural products O=C(C)[C@@H]1[C@@]2(C)[C@H]([C@H]3[C@@H]([C@]4(C)C(=CC(=O)CC4)CC3)CC2)CC1 RJKFOVLPORLFTN-STHVQZNPSA-N 0.000 abstract 1
- RJKFOVLPORLFTN-LEKSSAKUSA-N Syngestrets Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 1
- 206010046798 Uterine leiomyoma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
- 230000000069 prophylaxis Effects 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับองค์ประกอบทางเภสัชกรรมที่ประกอบรวมด้วยโพรเจสเทอโรน รีเซปเตอร์แอนตะกอนิสต์ กล่าวคือ (11B, 17B)-17-ไฮดรอกซี-11-[4-(เมทิลซัลโฟนิล)เฟนิล]-17- (เพนทาฟลูออโรเอทิล)เอสทรา-4,9-ไดอีน-3-โอน ที่ขนาดใช้ประมาณ 0.5 ถึง 5 มก. และโดยเฉพาะ ยิ่งกว่านี้ 2 มก. นอกจากนี้การประดิษฐ์นี้ยังเกี่ยวข้องกับการใช้องค์ประกอบทางเภสัชกรรมชนิดใหม่ สำหรับการรักษาและ/หรือการป้องกันโรคทางนรีเวชวิทยาอย่างเช่นไฟบรอยด์ของมดลูก (ไมโอมา, ไลโอไมโอมาของมดลูก), เยื่อบุมดลูกต่างที่ หรือการมีระดูมากเกิน และวิธีการทำให้ได้องค์ประกอบ ดังกล่าวและรูปแบบยาสำหรับให้ทางปาก สิทธิบัตรยา This invention relates to a pharmaceutical component that contains progesterone. Receptor anthraconist: (11B, 17B) -17-hydroxy-11- [4- (methylsulfonyl) phenyl] -17- (pentafluor Roethyl) estra-4,9-diene-3-transfer At a dose of 0.5 to 5 mg and preferably 2 mg, this invention also involves the use of a new pharmaceutical component. For the treatment and / or prophylaxis of gynecological diseases such as uterine fibroids (meoma, uterine lyophilis), uterine endometrium Or excessive menstruation And how to get the composition Such and the oral dosage form, patent medicine.
Claims (2)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH163150B TH163150B (en) | 2017-06-08 |
| TH163150A true TH163150A (en) | 2017-06-08 |
| TH1501006213A TH1501006213A (en) | 2017-06-08 |
Family
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