TH162735B - The use of PACAP to treat viral infections in aquatic organisms. - Google Patents
The use of PACAP to treat viral infections in aquatic organisms.Info
- Publication number
- TH162735B TH162735B TH1301002941A TH1301002941A TH162735B TH 162735 B TH162735 B TH 162735B TH 1301002941 A TH1301002941 A TH 1301002941A TH 1301002941 A TH1301002941 A TH 1301002941A TH 162735 B TH162735 B TH 162735B
- Authority
- TH
- Thailand
- Prior art keywords
- pacap
- organisms
- injection
- infected
- viruses
- Prior art date
Links
- 108060005172 MZB1 Proteins 0.000 title claims abstract 7
- 102000002808 Pituitary Adenylate Cyclase-Activating Polypeptide Human genes 0.000 title claims abstract 7
- 208000001756 Virus Disease Diseases 0.000 title abstract 3
- 206010047461 Viral infection Diseases 0.000 title 1
- 230000017613 viral reproduction Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 claims abstract 3
- 238000002347 injection Methods 0.000 claims abstract 3
- 239000007924 injection Substances 0.000 claims abstract 3
- 230000003612 virological Effects 0.000 claims abstract 2
- 230000000840 anti-viral Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 241000251468 Actinopterygii Species 0.000 abstract 1
- UDMBCSSLTHHNCD-KQYNXXCUSA-N Adenosine monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 abstract 1
- 230000003213 activating Effects 0.000 abstract 1
- 230000003247 decreasing Effects 0.000 abstract 1
- 201000009910 diseases by infectious agent Diseases 0.000 abstract 1
- 210000000056 organs Anatomy 0.000 abstract 1
- 230000001817 pituitary Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 238000003757 reverse transcription PCR Methods 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 230000004083 survival Effects 0.000 abstract 1
- 210000001519 tissues Anatomy 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับการใช้พิทูอิทรีอะดีนิเลตไซเคลสแอคทิเวติ้งโพลีเปปไทด์ (PACAP)ในการรักษาโรคไวรัสและโรคติดเชื้อที่เกิดจากไวรัสในสิ่งมีชีวิตในน้ำ PACAP ลำพับหรือ เมื่อรวมกับโมเลกุลด้านไวรัส แสดงประสิทธิภาพของมันโดยการเพิ่มการอยู่รอดของปลาหรือสัตว์น้ำ ที่มีเปลือกแข็งที่ติดเชื้อไว้รัสเมื่อมันถูกให้ทางปาก โดยการฉีดหรือ โดยอ่างฉีดหรือโดยอ่างแช่ นอกจากนี้มันยังถูก สังเกตุพบว่าสิ่งมีชีวิตที่ถูกทรีตรักษาหรือเพิ่มน้ำหนักของมันเมื่อเทียบกับสิ่งมีชีวิตที่ติดเชื้อและไม่ ถูกทรีต PACAP หรือสารรวมที่มี PACAP ลดจำนวนไวรัสในเนื้อเยื้อและอวัยวะที่อ่อนไหวต่อการ ติดเชื้อไวรัสตามที่มนถูกกำหนดโดย RT-PCR The invention involved the use of pituitary adenylate cyclas activating polypeptide. (PACAP) in the treatment of viral and infectious diseases caused by viruses in PACAP aquatic organisms or when combined with viral molecules. Show its effectiveness by increasing the survival of fish or aquatic life. The infected crust remains when it is given by mouth. By injection or By injection tub or by soaking tub It is also cheap. It was observed that the treated or treated organisms increased their weight compared to the infected and untreated organisms. PACAP or PACAP-containing aggregates decreased the number of viruses in the tissues and organs. Sensitive to Virus infection as defined by RT-PCR.
Claims (1)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH1301002941A TH1301002941A (en) | |
| TH162735A TH162735A (en) | 2017-05-25 |
| TH162735B true TH162735B (en) | 2017-05-25 |
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