TH162570B - Pyridazinone compound - Google Patents
Pyridazinone compoundInfo
- Publication number
- TH162570B TH162570B TH1001000180A TH1001000180A TH162570B TH 162570 B TH162570 B TH 162570B TH 1001000180 A TH1001000180 A TH 1001000180A TH 1001000180 A TH1001000180 A TH 1001000180A TH 162570 B TH162570 B TH 162570B
- Authority
- TH
- Thailand
- Prior art keywords
- ring
- aromatic ring
- pyridazinone compound
- group
- formula
- Prior art date
Links
- -1 Pyridazinone compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 238000006467 substitution reaction Methods 0.000 claims 1
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drugs Drugs 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เสนอสารประกอบซึ่งมีผลในการยับยั้ง PDE และมีประโยชน์ในฐานะตัวยา สำหรับการป้องกันหรือรักษาโรคจิตเภทหรืออื่น ๆ สารประกอบตามสูตร (I0) (สูตรเคมี) โดยที่ R1 แทน หมู่แทนที่ R2 แทน อะตอมของไฮโดรเจน หรือหมู่แทนที่ R3 แทน อะตอมของไฮโดรเจน หรือหมู่แทนที่ วงแหวน A แทน วงแหวนอะโรมาติกซึ่งสามารถถูกแทนที่ และ วงแหวน B แทน วงแหวนเฮเทอโรอะโรมาติกที่มีสมาชิก 5 ตำแหน่งซึ่งสามารถถูกแทนที่ หรือเกลือของสารดังกล่าว: The invention proposes a compound which has a PDE inhibitory effect and is useful as a drug. For the prevention or treatment of schizophrenia or other compounds according to the formula (I0) (chemical formula) where R1 represents the group instead of R2 represents the hydrogen atoms. Or a group instead of R3 for a hydrogen atom. Or a replaceable group. A ring represents an aromatic ring, which can be replaced, and a B ring, a hetero aromatic ring with a five-position member. Or salts of such substances:
Claims (1)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH1001000180A TH1001000180A (en) | |
| TH162570A TH162570A (en) | 2017-05-25 |
| TH162570B true TH162570B (en) | 2017-05-25 |
Family
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