TH160864B - 2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processes - Google Patents
2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processesInfo
- Publication number
- TH160864B TH160864B TH1501006546A TH1501006546A TH160864B TH 160864 B TH160864 B TH 160864B TH 1501006546 A TH1501006546 A TH 1501006546A TH 1501006546 A TH1501006546 A TH 1501006546A TH 160864 B TH160864 B TH 160864B
- Authority
- TH
- Thailand
- Prior art keywords
- chromene
- oxo
- hydrogen
- acetylcholine
- esters
- Prior art date
Links
- 229960004373 Acetylcholine Drugs 0.000 title abstract 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003869 acetamides Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 9
- 239000001257 hydrogen Substances 0.000 claims abstract 9
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims abstract 7
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 3
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 229910052736 halogen Inorganic materials 0.000 claims abstract 2
- 150000002367 halogens Chemical class 0.000 claims abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxyl anion Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- -1 methoxy, methyl Chemical group 0.000 claims 1
- 239000002329 esterase inhibitor Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบซึ่งมีถทธิ์ยับยั้งเอนไซม์อะเซติลโคลีนเอสเทอเรสชนิดใหม่ ที่มีสูตร (สูตร) ซึ่ง R1 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี หรือ ไฮดรอกซี R2 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี R3 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี หรือ ไนโตร หรือ ฮาโลเจน n เป็นจำนวนเต็มตั้งแต่ 0-3 The invention involved a new type of acetylcholine esterase inhibitor compound with the formula (formula), where R1 was hydrogen or C1-3 alkoxy or hydroxide. C. R2 is hydrogen or C1-3 Lcoxi R3 is hydrogen or C1-3 Lcoxi or nitro or halogen n is an integer from 0-3
Claims (2)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH160864B true TH160864B (en) | 2017-03-23 |
| TH160864A TH160864A (en) | 2017-03-23 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CU24572B1 (en) | COMPOUNDS DERIVED FROM 1,2,4-TRIAZOLONES 2,4,5-TRISUBSTITUTED | |
| SG10201809518QA (en) | Processes of preparing a jak1 inhibitor and new forms thereto | |
| EA201691799A1 (en) | BICYCLIC COMPOUNDS AS AUTOTAXIN PRODUCT INHIBITORS (ATX) AND LYSOPHOSPHATIDYLIC ACID INHIBITORS (LPA) | |
| EA201792021A1 (en) | JAK INHIBITOR | |
| RS54730B1 (en) | Inhibitors of beta-secretase | |
| EA201891278A1 (en) | HETEROCYCLIC INDOLS TO BE USED FOR INFECTION CAUSED BY THE FLU VIRUS | |
| MX2015017156A (en) | Bace inhibitors. | |
| EA201991241A1 (en) | METHOD FOR PRODUCING METHOXYMETHYLPYRIDINE DICARBOXYLATE | |
| EA201591915A1 (en) | COMPOUNDS OF PHENOXYETHYL DIHYDRO-1H-IZOHINOLINA | |
| EA201990238A1 (en) | Phosphorus-containing stimulants of sGC stimulants | |
| PH12019500875A1 (en) | Pyridone compound as c-met inhibitor | |
| TH160864B (en) | 2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processes | |
| CO2017001927A2 (en) | Crystalline forms of n- [3 - [(4ar, 7as) -2-amino-6- (5-fluoropyrimidin-2-yl) -4,4a, 5,7-tetrahydropyrrolo [3,4-d] [1, 3] thiazin-7a-yl] -4-fluoro-phenyl] -5-methoxy-pyrazine-2-carboxamide as bacterial inhibitors | |
| WO2016023522A3 (en) | Substituted phosphoramidate compounds and uses thereof | |
| WO2015173659A3 (en) | N-(3-oxo-2,3-dihydro-1 h-pyrazol-4-yl)-4,5-dihydronaphtho[2,1 -d]isoxazole-3-carboxamide derivatives and related compounds as smurf-1 inhibitors for the treatment of pulmonary arterial hypertension (pah) | |
| TH160864A (en) | 2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processes | |
| TH170304B (en) | Quinazolin-THF-Amine as a PDE1 inhibitor | |
| TH170304A (en) | Quinazolin-THF-Amine as a PDE1 inhibitor | |
| TH169348A (en) | Heterocyclic amide as a kinase inhibitor | |
| TH1701003446A (en) | Thieno derivatives[2,3-c]pyrol-4-transfer as an ERK inhibitor. | |
| TH171997A (en) | Hetero Eril and the use of that | |
| TH174565B (en) | Tetrahydropyranilbenzamide derivatives | |
| TH1701003178A (en) | Dihydropyrimidin-2-transfer compounds and its medical uses | |
| TH167853B (en) | Quinazoline-4 (3H) - Transfer Antibacterial | |
| TH168560B (en) | Antibacterial 2H-indazole derivative |