TH160864B - 2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processes - Google Patents
2- (2-oxo-2H-chromene-4-il) acetamide derivatives, which have an inhibitory effect on acetylcholine. Esters and manufacturing processesInfo
- Publication number
- TH160864B TH160864B TH1501006546A TH1501006546A TH160864B TH 160864 B TH160864 B TH 160864B TH 1501006546 A TH1501006546 A TH 1501006546A TH 1501006546 A TH1501006546 A TH 1501006546A TH 160864 B TH160864 B TH 160864B
- Authority
- TH
- Thailand
- Prior art keywords
- chromene
- oxo
- hydrogen
- acetylcholine
- esters
- Prior art date
Links
- 229960004373 Acetylcholine Drugs 0.000 title abstract 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003869 acetamides Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 9
- 239000001257 hydrogen Substances 0.000 claims abstract 9
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims abstract 7
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 3
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 229910052736 halogen Inorganic materials 0.000 claims abstract 2
- 150000002367 halogens Chemical class 0.000 claims abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxyl anion Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- -1 methoxy, methyl Chemical group 0.000 claims 1
- 239000002329 esterase inhibitor Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบซึ่งมีถทธิ์ยับยั้งเอนไซม์อะเซติลโคลีนเอสเทอเรสชนิดใหม่ ที่มีสูตร (สูตร) ซึ่ง R1 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี หรือ ไฮดรอกซี R2 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี R3 ได้แก่ ไฮโดรเจน หรือ C1-3 แอลคอกซี หรือ ไนโตร หรือ ฮาโลเจน n เป็นจำนวนเต็มตั้งแต่ 0-3 The invention involved a new type of acetylcholine esterase inhibitor compound with the formula (formula), where R1 was hydrogen or C1-3 alkoxy or hydroxide. C. R2 is hydrogen or C1-3 Lcoxi R3 is hydrogen or C1-3 Lcoxi or nitro or halogen n is an integer from 0-3
Claims (2)
Publications (2)
Publication Number | Publication Date |
---|---|
TH160864B true TH160864B (en) | 2017-03-23 |
TH160864A TH160864A (en) | 2017-03-23 |
Family
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