TH154822A - An aqueous eye drop solution based on cyclosporin A. - Google Patents
An aqueous eye drop solution based on cyclosporin A.Info
- Publication number
- TH154822A TH154822A TH1401004875A TH1401004875A TH154822A TH 154822 A TH154822 A TH 154822A TH 1401004875 A TH1401004875 A TH 1401004875A TH 1401004875 A TH1401004875 A TH 1401004875A TH 154822 A TH154822 A TH 154822A
- Authority
- TH
- Thailand
- Prior art keywords
- eye drop
- aqueous eye
- cyclosporin
- drop solution
- solution based
- Prior art date
Links
- 239000000243 solution Substances 0.000 title claims abstract 5
- 239000003889 eye drop Substances 0.000 title claims abstract 3
- PMATZTZNYRCHOR-CGLBZJNRSA-N (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17 Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
- 108010036949 Cyclosporine Proteins 0.000 title 1
- 229960001265 ciclosporin Drugs 0.000 title 1
- PMATZTZNYRCHOR-IMVLJIQESA-N 30-ethyl-33-[(E)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone Chemical compound CCC1NC(=O)C(C(O)C(C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(C(C)C)NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-IMVLJIQESA-N 0.000 claims abstract 4
- KIHBGTRZFAVZRV-UHFFFAOYSA-M 2-hydroxystearate Chemical compound CCCCCCCCCCCCCCCCC(O)C([O-])=O KIHBGTRZFAVZRV-UHFFFAOYSA-M 0.000 claims abstract 2
- 229960003444 IMMUNOSUPPRESSANTS Drugs 0.000 claims abstract 2
- 239000001913 cellulose Substances 0.000 claims abstract 2
- 229920002678 cellulose Polymers 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol Substances OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract 2
- 229940072106 hydroxystearate Drugs 0.000 claims abstract 2
- 230000001861 immunosuppresant Effects 0.000 claims abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 claims abstract 2
- 229920000642 polymer Polymers 0.000 claims abstract 2
- 229920002554 vinyl polymer Polymers 0.000 claims abstract 2
Abstract
DC60 (07/10/57) การประดิษฐ์นี้เกี่ยวข้องกับสารละลายหยอดตาชนิดในน้ำซึ่งประกอบด้วยสารกดภูมิคุ้มกัน อาทิเช่น ซิโคลสปอริน A (Ciclosporin A) และโพลิเมอร์อย่างน้อยสามชนิด ทางที่ดีสารละลายดังกล่าวควรเป็น สารรวมของอนุพันธ์เซลลูโลส อนุพันธ์โพลิไวนิล และแมโครกอลกลีเซอรอลไฮดรอกซีสเตียเรต สิทธิบัตรยา DC60 (07/10/57) The invention involved an aqueous eye drop solution containing immunosuppressants such as ciclosporin A (Ciclosporin A) and at least three polymers. Ideally, the solution should be Aggregate of cellulose derivatives Polyvinyl derivatives And macro-glycerol, hydroxystearate, patent drug
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH154822A true TH154822A (en) | 2016-08-01 |
Family
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