TH152504A - Treatment of postpartum hemorrhage with chemically modified heparin or heparin sulfate. And drugs to stimulate uterine contractions - Google Patents
Treatment of postpartum hemorrhage with chemically modified heparin or heparin sulfate. And drugs to stimulate uterine contractionsInfo
- Publication number
- TH152504A TH152504A TH1401006510A TH1401006510A TH152504A TH 152504 A TH152504 A TH 152504A TH 1401006510 A TH1401006510 A TH 1401006510A TH 1401006510 A TH1401006510 A TH 1401006510A TH 152504 A TH152504 A TH 152504A
- Authority
- TH
- Thailand
- Prior art keywords
- uterus
- treatment
- sulfate
- postpartum hemorrhage
- heparin
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract 7
- 229940079593 drugs Drugs 0.000 title claims abstract 7
- 206010036417 Postpartum haemorrhage Diseases 0.000 title claims abstract 5
- ZFGMDIBRIDKWMY-PASTXAENSA-N Heparin Chemical class CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims 2
- 229920002971 Heparan sulfate Polymers 0.000 title 1
- 206010049975 Uterine contractions during pregnancy Diseases 0.000 title 1
- 210000004291 Uterus Anatomy 0.000 claims abstract 8
- 229920002683 Glycosaminoglycan Polymers 0.000 claims abstract 6
- 210000004204 Blood Vessels Anatomy 0.000 claims abstract 4
- 210000000754 Myometrium Anatomy 0.000 claims abstract 4
- 239000000203 mixture Substances 0.000 claims abstract 4
- 230000014508 negative regulation of coagulation Effects 0.000 claims abstract 4
- 230000002265 prevention Effects 0.000 claims abstract 4
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract 4
- 206010018987 Haemorrhage Diseases 0.000 claims abstract 2
- 230000000740 bleeding Effects 0.000 claims abstract 2
- 231100000319 bleeding Toxicity 0.000 claims abstract 2
- 230000000694 effects Effects 0.000 claims 3
- WKPUACLQLIIVJJ-RHKLHVFKSA-M (2S,3R,4R,5S,6R)-4-hydroxy-3-methoxy-6-[(2S,3R,4S,5S,6R)-6-methoxy-4-oxido-5-(sulfooxyamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-5-sulfooxyoxane-2-carboxylate Chemical class [O-][C@H]1[C@H](NOS(O)(=O)=O)[C@H](OC)O[C@@H](COS(O)(=O)=O)[C@@H]1O[C@H]1[C@@H](OS(O)(=O)=O)[C@H](O)[C@@H](OC)[C@@H](C([O-])=O)O1 WKPUACLQLIIVJJ-RHKLHVFKSA-M 0.000 claims 1
- 210000004369 Blood Anatomy 0.000 claims 1
- 229960002897 Heparin Drugs 0.000 claims 1
- 241000196435 Prunus domestica subsp. insititia Species 0.000 claims 1
- 230000002429 anti-coagulation Effects 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 150000004676 glycans Polymers 0.000 claims 1
- 229920000669 heparin Polymers 0.000 claims 1
- 150000004804 polysaccharides Polymers 0.000 claims 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
Abstract
DC60 (23/12/57) การประดิษฐ์นี้จะอ้างอิงถึงการใช้ของซัลเฟเทดไกลโคซามิโนไกลแคนบางชนิดสำหรับ การบำบัดรักษา หรือ การป้องกันของภาวะตกเลือดหลังคลอด ซัลเฟเทดไกลโคซามิโนไกลแคน จะมีแอคติวิตี้ต้านการแข็งตัวของเลือดที่ลดลง และถูกให้ในการรวมกันกับยากระตุ้นการหดตัว ของมดลูกอย่างน้อยหนึ่งชนิดที่สามารถสนับสนุนการหดรัดตัวของกล้ามเนื้อมดลูกของมดลูกได้ และด้วยเหตุนี้จะบีบหลอดเลือด และหยุดการตกเลือด การประดิษฐ์นี้จะอ้างอิงถึงการใช้ของซัลเฟเทไกลไคซามิโนไกลโคซามิโนไกลแคนบางชนิดสำหรับ การบำบัดรักษา หรือ การป้องกันของภาวะตกเลือดหลังคลอด ซัลเฟเทดไกลโคซามิโนไกลแคน จะมีแอคติวิตี้ต้านการแข็งตัวของเลือดที่ลดลง และถูกให้ในการรวมกันกับยากระตุ้นการหดตัว ของมดลูกอย่างน้อยหนึ่งชนิดที่สามารถสนับสนุนการหดรัดตัวของกล้ามเนื้อมดลูกของมดลูก และด้วย้หตุนี้จะบีบหลอดเลือด และหยุดการจกเลือด สิทธิบัตรยา DC60 (23/12/57) This invention makes reference to the use of certain types of sulfate glycosaminoglycans for Treatment or prevention of postpartum hemorrhage. Sulfated Glycosamino Glycan There will be a decrease in anticoagulant activity. And was given in combination with stimulant drugs At least one type of uterus that can support the contraction of the uterine muscles of the uterus. And thereby squeeze the blood vessels And stop bleeding This invention refers to the use of some types of sulfate glycosaminoglycosaminoglycans for Treatment or prevention of postpartum hemorrhage. Sulfated Glycosamino Glycan There will be a decrease in anticoagulant activity. And was given in combination with stimulant drugs At least one type of uterus that can support the contraction of the uterine muscles of the uterus. And with this stimulus it will squeeze the blood vessels And stop the drug patent blood coagulation
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH1401006510A TH1401006510A (en) | 2016-05-19 |
| TH152504A true TH152504A (en) | 2016-05-19 |
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