TH14976A - How to use 7-halos- and 78-methano-taxall anti-tumor agents? And pharmaceutical mixtures containing those substances - Google Patents

Abstract

The invention provided the 7-eoxi-7-taxol of formula I (chemical formula), formula I (including II and III), was used for cancer. The same types that taxol has shown to be effective, include ovarian cancer, breast cancer, and malignant melanoma as well as lung cancer. Stomach, colon cancer, head and neck cancer and human leukemia drug patent.

Claims (1)

1. Compound Formula I; (Chemical Formula) where: R1 is selected from a group containing (Chemical Formula) R3 is selected from a group containing -H, -NHC (O) Phenyl or -NHC (O) OC (CH3) 3; With all the definitions that either R2 and R3 are -H, R2 and R3 are both non -H; R4 is -H or selected from a group containing (chemical formula) R5 is -H or -OH, with all requirements that Where R5 is -OH, R4 is -H, and with another requirement that when R5 is -H, R4 is any other than -H; R6 is -H; -H when R7 is (chemical formula) R6 is -H; -H when R7 is (chemical formula), R10 is -H. Tag: drug patent.