TH13706B - Controlled release formula containing tramadol - Google Patents

Abstract

This invention has a line side leakage detecting current meter or neutral neutral. It consists of a power supply unit (POWER SUPPLY) for supplying power to circuits and circuits inside the chassis. The circuit consists of a current sensor (CURRENT TRANSFORMER or "CT") for connection to the transmission line to detect the blue wave waveform. Leakages occurring in power transmission lines To forward the signal to the amplifying unit (AMPLIFIER) for amplifying the signal stronger before forwarding it to the microcontroller (CPU) to process the value. Leakage current Leakage characteristics of the signal waveform are measured by the nature of the signal waveform. Different types of leakage currents Obtained from the signal amplifier (AMPLIFIER) and will display the quantity Leakage current From the processing of the microcontroller unit (CPU) through the display unit (DISPLAY) and the leak characteristics from the microcontroller unit (CPU) process the measured waveform compared to the recorded base data waveform. The processor's memory displays different color-changing LED lamps corresponding to the current waveform. That the microcontroller (CPU) can process, red is the leakage current, the earth wire, green is the leakage current, the neutral-to-earth line. Orange is a mixed fault current between the line and the earthed neutrals, and the power supply unit supplies power to the circuit.

Claims (7)

1.Controlled pharmaceutical drug And give medicine by mouth Which is suitable for dosing every 12 hours, contains 50 to 400 mg of tramadol or pharmacologically acceptable salt (calculated as tramadol hydrochloride) in a matrix ( metrix) that releases a controlled matrix containing 1 and 80% by weight / weight of one or more of the hydrophobic or hydrophobic polymers. Cellulose ether is commonly used and which has the following solubility rates. In experiments under laboratory conditions, when they were measured using the PH. Eu r. Paddle method at 100 rpm in 900 ml, 0.1 nh hydrochloric acid at 37 ° C and using UV measurements. At 270 nm, between 5 and 50% (by weight), the tramadol released after 1 hour, between 10 and 75% (by weight), the tramadol released after 2 hours, between 20 and 95. % (By weight) Tramadol released after 4 hours Between 40 and 100% (by weight) Tramadol released after 8 hours More than 50% (by weight) Tramadol. Released after 12 hours More than 70% (by weight) Tramadol released after 18 hours More than 80% (by weight) Tramadol released after 24 hours. 2. Dosage pattern according to claim 1, a special characteristic in which the controlled release matrix contains cellulose ether which is an alkyl cellulose. 3. Dosage form according to any one of claim 1, special effects in which Controlled release matrix containing at least one alkyl. Popular are C1 - C6, alkyl cellulose, and at least C12-C36, commonly used C14-C22, aliphatic alcohol. And the alternative trait is, at the very least, polyalkyl glycol, commonly used is polyethylene glycol. 4. Dosage form according to claim 3, special effects in which at least L. Kylcellulose is Ethyl cellulose 5. Dosage form according to claim 3 or 4, special effects in which size form Medicines containing one or more alkyl cellulose from 1 to 20% weight / weight, commonly used is 2 to 15%. 6. Dosage form according to any of Claim 3 to 5, special effects in Which aliphatic alcohol contains lauryl alcohol, myristyl alcohol, stearyl alcohol Or popular is Cetyl alcohol Or sitostearyl alcohol 7. Dosage form according to any of Claims 3 to 6, special effects in The dosage forms contain aliphatic alcohol from 5 to 30% w / w, most commonly used aliphatic alcohol from 10 to 25% w / w.