TH13641EX - Benzopyran and antagonis of LTB4 correlated - Google Patents

Abstract

Benzopyran and antagonis of leucotriene, B4, are other ringfugees whose formula ## is the chemical formula ... I, where R to the power of 1 is fane. The nil or phenyl group with its substitutions and A, n, R to the power of 2 and R to the power of 3 is given here.

Claims (1)

1. Compound formula ## is the chemical formula ... I, where A is O, CH2, S, NH or N (C1-C6 alkyl); n is zero, 1 or 2 R to the power of 1 is the substitution group at the b or c position of the formula ## is the chemical formula R to the 2 power, R to the 8 power, R to the 9 power, and R to the 10 power, or Independently of each other is One or two groups of the following: Fluoro, Chloro, C1-C6 alkyl, C1-C6 Alkoxi, C1-C4 Perfluoroalc, C1-C6 alkyl Lthio, C1-C6 alkylsulfenyl or C1-C6 alkylsulfonyl R raised to the power of 3 is - (CH2) qCHR raised to the power of 11 R to the power of 12, - (CH2) qR. Exponent 12, -O (CH