TH134786B - Crystalline form of benzyl benzene inhibitor for SGLT2. - Google Patents
Crystalline form of benzyl benzene inhibitor for SGLT2.Info
- Publication number
- TH134786B TH134786B TH1201006410A TH1201006410A TH134786B TH 134786 B TH134786 B TH 134786B TH 1201006410 A TH1201006410 A TH 1201006410A TH 1201006410 A TH1201006410 A TH 1201006410A TH 134786 B TH134786 B TH 134786B
- Authority
- TH
- Thailand
- Prior art keywords
- sglt2
- crystalline form
- benzyl benzene
- inhibitor
- crystalline compounds
- Prior art date
Links
- 102100016749 SLC5A2 Human genes 0.000 title abstract 3
- 101710040674 SLC5A2 Proteins 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 title abstract 3
- CZZYITDELCSZES-UHFFFAOYSA-N Diphenylmethane Chemical compound C=1C=CC=CC=1CC1=CC=CC=C1 CZZYITDELCSZES-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 102000003673 Symporters Human genes 0.000 abstract 1
- 108090000088 Symporters Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000005426 pharmaceutical component Substances 0.000 abstract 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Abstract
ที่ได้รับการจัดเตรียมเป็นรูปผลึกของสารประกอบซึ่งมีผลซึ่งยับยั้งต่อตัวขนส่งร่วมกลูโคส ที่ขึ้นอยู่กับโซเดียม SGLT2 การประดิษฐ์ยังจัดเตรียมองค์ประกอบทางเภสัชกรรม,วิธีซึ่ง ประกอบด้วยการเตรียมสารประกอบที่เป็นผลึก,และวิธีของการใช้สารประกอบที่เป็นผลึก,อย่าง อิสระหรือในการรวมก้นกับตัวกระทำทางการรักษาอื่นๆ,สำหรับการบำบัดโรคและภาวะซึ่งได้รับ ผลโดยการยับยั้ง SGLT หรือห SGLT2 The prepared compounds are crystalline compounds that have inhibitory effects on the glucose co-transporter. That is based on sodium SGLT2.The invention also provides a pharmaceutical component, a method in which Consists of preparation of crystalline compounds, and methods of application of crystalline compounds, such as Independent or in combination with other therapeutic agents, for the treatment of diseases and conditions which have Effects by inhibiting SGLT or SGLT2.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH134786B true TH134786B (en) | 2014-06-11 |
| TH134786A TH134786A (en) | 2014-06-11 |
Family
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