TH132948A - An indazole derivative (INDAZOLE DERIVATIVES), which is replaced by an active As a kinase inhibitor (KINASE INHIBITORS) - Google Patents
An indazole derivative (INDAZOLE DERIVATIVES), which is replaced by an active As a kinase inhibitor (KINASE INHIBITORS)Info
- Publication number
- TH132948A TH132948A TH801001539A TH0801001539A TH132948A TH 132948 A TH132948 A TH 132948A TH 801001539 A TH801001539 A TH 801001539A TH 0801001539 A TH0801001539 A TH 0801001539A TH 132948 A TH132948 A TH 132948A
- Authority
- TH
- Thailand
- Prior art keywords
- substance
- indazole
- diseases
- details
- pharmaceutical composition
- Prior art date
Links
- 229940043355 kinase inhibitor Drugs 0.000 title 2
- 239000003757 phosphotransferase inhibitor Substances 0.000 title 2
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 150000002473 indoazoles Chemical class 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 11
- 201000010099 disease Diseases 0.000 claims abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 4
- 125000003453 indazolyl group Chemical class N1N=C(C2=C1C=CC=C2)* 0.000 claims abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 4
- 102000004169 proteins and genes Human genes 0.000 claims abstract 4
- 108090000623 proteins and genes Proteins 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 206010028980 Neoplasm Diseases 0.000 claims abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 claims abstract 2
- 201000011510 cancer Diseases 0.000 claims abstract 2
- 102000020233 phosphotransferase Human genes 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
Abstract
DC60(08/10/51) สารอนุพันธ์อินดาโซลซึ่งถูกแทนที่ของสูตร(I)และเกลือที่สามารถยอมรับได้ทางเภสัชกรรม ของสารนั้นดังที่ถูกนิยามไว้ในรายละเอียดการประดิษฐ์,กระบวนการสำหรับการเตรียมสารนั้นและ องค์ประกอบทางเภสัชกรรมที่ประกอบด้วยสารเหล่านั้นได้ถูกเปิดเผยไว้สารประกอบของการ ประดิษฐ์อาจใช้ประโยชน์ได้ในการรักษาในการบำบัดของโรคที่เกิดร่วมกับการทำหน้าที่ของโปรตีน ไคเนสที่ไม่ถูกควบคุมเช่นมะเร็ง สารอนุพันธ์อินดาโซลซึ่งถูกแทนที่ของสูตร(I)และเกลือที่สามารถรับได้ทางเภสัชกรรม ของสารนั้นดังที่ถูกนิยามไว้ในรายละเอียดการประดิษฐ์,กระบวนการสำหรับการเตรียมสารนั้นและ องค์ประกอบทางเภสัชกรรมที่ประกอบด้วยสารเหล่านั้นได้ถูกเปิดเผยไว้สารประกอบของการ ประดิษฐ์อาขใช้ประโยชน์ได้ในการรักษาในการบำบัดของโรคที่เกิดร่วมกับการทำหน้าที่ของโปรตีน DC60(08/10/08) Substituted indazole derivative of formula (I) and pharmaceutically acceptable salt. of that substance as defined in the details of the invention, the process for preparing that substance and The pharmaceutical composition containing those substances has been disclosed. The artificial substance may be useful in the treatment of diseases that occur with the function of proteins. Unregulated kinases such as cancer Substituted indazole derivatives of formula (I) and pharmaceutically available salts. of that substance as defined in the details of the invention, the process for preparing that substance and The pharmaceutical composition containing those substances has been disclosed. Pradit Akha can be used in the treatment of diseases that occur with the function of proteins.
Claims (1)
Publications (3)
| Publication Number | Publication Date |
|---|---|
| TH95964A TH95964A (en) | 2009-05-29 |
| TH95964B TH95964B (en) | 2014-04-28 |
| TH132948A true TH132948A (en) | 2014-04-28 |
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