TH131334A - Synthesis of magnol and its analogues - Google Patents
Synthesis of magnol and its analoguesInfo
- Publication number
- TH131334A TH131334A TH1201004266A TH1201004266A TH131334A TH 131334 A TH131334 A TH 131334A TH 1201004266 A TH1201004266 A TH 1201004266A TH 1201004266 A TH1201004266 A TH 1201004266A TH 131334 A TH131334 A TH 131334A
- Authority
- TH
- Thailand
- Prior art keywords
- derivatives
- analogues
- magnolol
- diol
- formula
- Prior art date
Links
- XVOKPNRYHDZDMX-UHFFFAOYSA-N 1-(4-ethyl-2-bicyclo[2.2.1]heptanyl)cyclohexan-1-ol Chemical compound C1C(CC)(C2)CCC1C2C1(O)CCCCC1 XVOKPNRYHDZDMX-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 6
- 238000004519 manufacturing process Methods 0.000 claims abstract 3
- 150000001875 compounds Chemical class 0.000 claims 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 abstract 16
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 8
- 238000000034 method Methods 0.000 abstract 3
- 238000009795 derivation Methods 0.000 abstract 2
Abstract
DC60(30/09/56) วิธีที่บรรยายสำหรับการผลิตแมกโนลอล(Magnolol),หรืออนุพันธ์หรือสารคล้ายคลึงของ สารดังกล่าววิธีรวมถึงการได้มาของMOMอีเธอร์ของ5,5'ไดแอลลิลไบฟีนิล2,2'ไดออลหรือ อนุพันธ์หรือสารคล้ายคลึงของสารดังกล่าวและจากนั้นเปลี่ยนMOMอีเธอร์ของ5,5'ไดแอลลิล ไบฟีนิล2,2'ไดออลไปเป็นแมกโนลอลหรืออนุพันธ์หรือสารคล้ายคลึงของสารดังกล่าว วิธีที่บรรยายสำหรับการผลิตแมกโนลอล,หรืออนุพันธ์หรือสารคล้ายคลึงของสารดังกล่าว วิธีรวมถึงการได้มาของMOMอีเธอร์ของ5,5'ไดแอลลิลไบฟีนิล2,2'ไดออลหรืออนุพันธ์หรือสาร คล้ายคลึงของสารดังกล่าวและจากนั้นเปลี่ยนMOMอีเธอร์ของ5,5'ไดแอลลิลไบฟีนิล2,2'ไดออล ไปเป็นแมกโนลอลหรืออนุพันธ์หรือสารคล้ายคลึงของสารดังกล่าว DC60(30/09/13) Method described for the production of Magnolol, or its derivatives or analogs. Such substances include the derivation of MOM ether of 5,5'diallylbiphenyl2,2'diol or derivatives or analogues thereof and then convert the MOM ether of 5,5'diallyl Biphenyl2,2'diol to magnolol or derivatives or analogs thereof. Methods described for the production of magnolol, or derivatives or analogs thereof. The method includes the derivation of MOM ether of 5,5'diallylbiphenyl2,2'diol or derivatives or substances. Analogue of such substance and then change MOM ether of 5,5'diallylbiphenyl2,2'diol. to magnolol or its derivatives or analogues.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH131334B TH131334B (en) | 2014-02-27 |
| TH131334A true TH131334A (en) | 2014-02-27 |
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