TH124353B - An eye component that is based on omega-3 and omega-6 fatty acid polyan saturates. - Google Patents
An eye component that is based on omega-3 and omega-6 fatty acid polyan saturates.Info
- Publication number
- TH124353B TH124353B TH1101002079A TH1101002079A TH124353B TH 124353 B TH124353 B TH 124353B TH 1101002079 A TH1101002079 A TH 1101002079A TH 1101002079 A TH1101002079 A TH 1101002079A TH 124353 B TH124353 B TH 124353B
- Authority
- TH
- Thailand
- Prior art keywords
- omega
- fatty acid
- acid
- polyan
- saturates
- Prior art date
Links
- 235000020660 omega-3 fatty acid Nutrition 0.000 title claims abstract 3
- 235000020665 omega-6 fatty acid Nutrition 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 claims abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 229940067631 Phospholipids Drugs 0.000 claims 1
- 229940046009 Vitamin E Drugs 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 125000004432 carbon atoms Chemical group C* 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 235000021085 polyunsaturated fats Nutrition 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 150000003712 vitamin E derivatives Chemical class 0.000 claims 1
- MBMBGCFOFBJSGT-KUBAVDMBSA-N Docosahexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 2
- 229960004363 doconexent Drugs 0.000 abstract 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 2
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 2
- ZCDMRPMKAQLWAO-PZLFCYFRSA-N (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid;(9Z,12Z)-octadeca-9,12-dienoic acid Chemical class CCCCC\C=C/C\C=C/CCCCCCCC(O)=O.CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O ZCDMRPMKAQLWAO-PZLFCYFRSA-N 0.000 abstract 1
- 206010010741 Conjunctivitis Diseases 0.000 abstract 1
- 210000004087 Cornea Anatomy 0.000 abstract 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-α-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 abstract 1
- 206010013774 Dry eye Diseases 0.000 abstract 1
- 229960005135 Eicosapentaenoic Acid Drugs 0.000 abstract 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N Eicosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 1
- 229940012843 Omega-3 Fatty Acids Drugs 0.000 abstract 1
- 229940033080 Omega-6 Fatty Acids Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002378 acidificating Effects 0.000 abstract 1
- 229960001452 alpha-Tocopherol Acetate Drugs 0.000 abstract 1
- 239000000607 artificial tear Substances 0.000 abstract 1
- 239000012267 brine Substances 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 235000020664 gamma-linolenic acid Nutrition 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000699 topical Effects 0.000 abstract 1
Abstract
การประดิษฐ์เกี่ยวข้องกับองค์ประกอบที่ใช้เฉพาะที่สำหรับการป้องกันและการรักษาพยาธิวิทยาเกี่ยวกับดวงตา,โดยเฉพาะกระจกตาและเยื่อตาอักเสบและกลุ่มอาการตาแห้ง,ซึ่งมี,เป็นส่วนผสมออกฤทธิ์,พอลิอันแซทจูเรเทด แฟทที แอซิดชนิดโอเมกา-3และโอเมกา-6,และอย่างจำเพาะคือ EPA(ไอโคซะเพนทะอีนออิค แอซิด),DHA(โดโคซะเฮกซะอีนออิค แอซิด)และGLA(y-ลินอเลนิค แอซิด),ซึ่งผสมกับวิตามินEแอซิเททและเตรียมสูตรผสมในองค์ประกอบที่เสถียรในไฮโดรเจล,นั่นคือในรูปที่กระจายตัวแล้วในน้ำกระสายยาแอเควียสที่มีพอลิเมอร์ก่อเจลหนึ่งชนิดหรือมากกว่าองค์ประกอบที่เสนอไว้ถูกบ่งชี้โดยเฉพาะสำหรับใช้เป็นน้ำตาเทียม The invention involves a topical component for the prevention and treatment of ocular pathology, in particular cornea and conjunctivitis and dry eye syndrome, in which, as an active ingredient, polyaneshaturated. Omega-3 and omega-6 fatty acids, and specifically EPA (Icosapentaenoic Acid), DHA (Docosahexaenoic Acid) and GLA (y-linolenic Acid), which was mixed with vitamin E acetate and was formulated in a stable constituent in hydrogels, that is, in a dispersed form in a polymer-containing acidic acid brine. One or more gels of the proposed components are specifically indicated for use as artificial tears.
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH124353B true TH124353B (en) | 2013-06-06 |
TH124353A TH124353A (en) | 2013-06-06 |
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