TH123682B - Cholesterol ester transfer protein inhibitor (CETP) compound - Google Patents
Cholesterol ester transfer protein inhibitor (CETP) compoundInfo
- Publication number
- TH123682B TH123682B TH801005670A TH0801005670A TH123682B TH 123682 B TH123682 B TH 123682B TH 801005670 A TH801005670 A TH 801005670A TH 0801005670 A TH0801005670 A TH 0801005670A TH 123682 B TH123682 B TH 123682B
- Authority
- TH
- Thailand
- Prior art keywords
- cetp
- compound
- alkyl
- transfer protein
- cholesterol ester
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title abstract 3
- 239000000126 substance Substances 0.000 claims abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- -1 notro Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000001589 carboacyl group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000003573 thiols Chemical class 0.000 claims 1
- 102100019883 CETP Human genes 0.000 abstract 2
- 101700077539 CETP Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Abstract
การประดิษฐ์ครั้งนี้จะจัดหาสารประกอบตามสูตร (I) (สูตรเคมี) (I) โดยที่ตัวแปร R1, R2, R3, R4, R5, R6, R7 คือดังที่นิยามไว้ในที่นี้, โดยที่สารประกอบดังกล่าวคือ สารยับยั้ง CETP, และดังนั้นจะสามารถถูกใช้สำหรับการบำบัดความผิดปกติหรือโรคที่สื่อโดย CETP หรือที่ตอบสนองต่อการยับยั้งของ CETP: This invention provides a compound according to the formula (I) (chemical formula) (I) where the variables R1, R2, R3, R4, R5, R6, R7 are as defined here, where the compound is a substance. CETP inhibitors, and therefore can be used for the treatment of disorders or diseases conveyed by CETP or that respond to CETP inhibition:
Claims (1)
Publications (2)
Publication Number | Publication Date |
---|---|
TH123682B true TH123682B (en) | 2013-05-23 |
TH123682A TH123682A (en) | 2013-05-23 |
Family
ID=
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