TH118572B - Corynebacterium microorganisms with the development of 5'-inosinic acid and bioavailability in the production of nucleic acids by using drycrynebacterium microbes - Google Patents
Corynebacterium microorganisms with the development of 5'-inosinic acid and bioavailability in the production of nucleic acids by using drycrynebacterium microbesInfo
- Publication number
- TH118572B TH118572B TH1101002442A TH1101002442A TH118572B TH 118572 B TH118572 B TH 118572B TH 1101002442 A TH1101002442 A TH 1101002442A TH 1101002442 A TH1101002442 A TH 1101002442A TH 118572 B TH118572 B TH 118572B
- Authority
- TH
- Thailand
- Prior art keywords
- inosinic acid
- development
- production
- drycrynebacterium
- microbes
- Prior art date
Links
- 241000186216 Corynebacterium Species 0.000 title claims abstract 4
- 244000005700 microbiome Species 0.000 title claims abstract 3
- 230000036912 Bioavailability Effects 0.000 title 1
- GRSZFWQUAKGDAV-KQYNXXCUSA-N Inosinic acid Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-KQYNXXCUSA-N 0.000 title 1
- 244000052616 bacterial pathogens Species 0.000 title 1
- 230000035514 bioavailability Effects 0.000 title 1
- 235000013902 inosinic acid Nutrition 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 claims abstract 5
- 108090000790 Enzymes Proteins 0.000 claims abstract 5
- CDEWYZPQOSTQOQ-VQFZJOCSSA-N [C@@H]1([C@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O1)N1C=NC=2C(O)=NC=NC12.[C@@H]1([C@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O1)N1C=NC=2C(O)=NC=NC12 Chemical compound [C@@H]1([C@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O1)N1C=NC=2C(O)=NC=NC12.[C@@H]1([C@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O1)N1C=NC=2C(O)=NC=NC12 CDEWYZPQOSTQOQ-VQFZJOCSSA-N 0.000 claims abstract 4
- KDCGOANMDULRCW-UHFFFAOYSA-N Purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 claims abstract 3
- 230000037348 biosynthesis Effects 0.000 claims abstract 3
- 230000015572 biosynthetic process Effects 0.000 claims abstract 3
- 230000014509 gene expression Effects 0.000 claims abstract 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K [O-]P([O-])([O-])=O Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- PPQRONHOSHZGFQ-LMVFSUKVSA-N aldehydo-D-ribose 5-phosphate Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PPQRONHOSHZGFQ-LMVFSUKVSA-N 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 abstract 1
Abstract
การประดิษฐ์นี้นำเสนอเกี่ยวข้องกับจุลินทรีย์สกุลโครี่เนแบคทีเรี่ยม(Corynebacterium) ผลิต 5'-อิโนซินิก แอซิด(5'-inosinic acid)ในการแสดงออกของยีนซึ่งเข้ารหัสเอนไซม์สัมพันธ์ การสังเคราะห์ชีวภาพพิวรีน(purine biosynthesis related enzyme)เพิ่มสูงกว่าการแสดงออกอยู่ ภายใน และเกี่ยวข้องกับวิธีการหนึ่งในการผลิต 5'-อิโนซินิก แอซิด (5'-inosinic acid) ประกอบด้วยการเพาะเชื้อจุลินทรีย์สกุลโครี่เนเบคทีเรี่ยม (Corynebacterium)ด้วยการพัฒนาผลิต ภาพ 5'-อิโนซินิก แอซิด (5'-inosinic acid) The proposed invention relates to the Corynebacterium genus producing 5'-inosinic acid (5'-inosinic acid). acid) in gene expression which encodes the associated enzyme. Purine biosynthesis related enzyme is higher than intrinsic expression and involves a method for the production of 5'-inosinic acid (5'-inosinic acid). Microorganisms of the genus Cory, Nebectirium (Corynebacterium) with the development of 5'-inosinic acid (5'-inosinic acid) productivity.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH118572B true TH118572B (en) | 2012-12-27 |
| TH118572A TH118572A (en) | 2012-12-27 |
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