TH104491B - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- TH104491B TH104491B TH801004935A TH0801004935A TH104491B TH 104491 B TH104491 B TH 104491B TH 801004935 A TH801004935 A TH 801004935A TH 0801004935 A TH0801004935 A TH 0801004935A TH 104491 B TH104491 B TH 104491B
- Authority
- TH
- Thailand
- Prior art keywords
- quinoline derivatives
- derivative
- nrcc
- nhc
- formula
- Prior art date
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000005013 2-aminoquinolines Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000005426 pharmaceutical component Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 108010006590 serotonin 5 receptor Proteins 0.000 abstract 1
Abstract
การประดิษฐ์นี้จะเกี่ยวข้องกับอนุพันธ์ของ 2-อะมิโนควิโนลีน ซึ่งจะถูกแสดงให้เห็น สูตรทั่วไป I (สูตรเคมี) I ซึ่ง R1, R2 และ R3 คือ ดังที่ถูกนิยามในรายละเอียดการประดิษฐ์ ที่เป็น 5-HT5A รีเซพเตอร์ แอนทาโกนิสท์, การผลิตของอนุพันธ์เหล่านี้, องค์ประกอบทางเภสัชกรรมที่มีอนุพันธ์เหล่านี้ และ การใช้ของอนุพันธ์เหล่านี้ในฐานะเป็นยาเวชภัณฑ์ This invention is related to the derivative of 2- aminoquinoline It is shown that the general formula I (chemical formula) I, where R1, R2 and R3 are, as defined in the description of the invention as 5-HT5A receptor antagonist, the production of the derivative. These, the pharmaceutical components containing these derivatives and their use as a pharmaceutical drug.
Claims (1)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH104491B true TH104491B (en) | 2010-10-12 |
| TH104491A TH104491A (en) | 2010-10-12 |
Family
ID=
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