TH102404A - A method of using substituted piperidine which enhances the action of P53. - Google Patents
A method of using substituted piperidine which enhances the action of P53.Info
- Publication number
- TH102404A TH102404A TH701003261A TH0701003261A TH102404A TH 102404 A TH102404 A TH 102404A TH 701003261 A TH701003261 A TH 701003261A TH 0701003261 A TH0701003261 A TH 0701003261A TH 102404 A TH102404 A TH 102404A
- Authority
- TH
- Thailand
- Prior art keywords
- chemical formula
- associated disease
- hdm2
- enhances
- action
- Prior art date
Links
- 150000003053 piperidines Chemical class 0.000 title 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N tetrahydropyridine hydrochloride Natural products C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 239000000126 substance Substances 0.000 claims 16
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 6
- 102100032257 E3 ubiquitin-protein ligase Mdm2 Human genes 0.000 abstract 2
- 108050002772 E3 ubiquitin-protein ligase Mdm2 Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
Abstract
DC60 (07/08/50) ประดิษฐ์ปัจจุบันเปิดเผยวิธีการของการใช้สารประกอบซึ่งมีการออกฤทธิ์เป็นตัวต้าน โปรตีน HDM2, เพื่อบำบัดหรือป้องกันมะเร็ง, โรคอื่นที่มีสาเหตุจากการงอกขยายของเซลล์ อย่างผิดปรกติ, โรคซึ่งร่วมกับ HDM2, หรือโรคซึ่งร่วมกับการออกฤทธิ์ของ P53 อย่างไม่สม่ำเสมอ ประดิษฐ์ปัจจุบันเปิดเผยวิธีการของการใช้สารประกอบซึ่งมีการออกฤทธิ์เป็นตัวต้าน โปรตีน HDM2, เพื่อบำบัดหรือป้องกันมะเร็ง, โรคอื่นที่มีสาเหตุจากการงอกขยายจของเซลล์ อย่างผิดปกติ, โรคซึ่งร่วมกับ HDM2, หรือโรคซึ่งร่วมกับการออกฤทธิ์ของ P53 อย่างไม่สม่ำเสมอ สิทธิบัตรยา DC60 (07/08/50) currently invention discloses a method for the use of active compounds as an anti-HDM2 protein, to treat or prevent cancer, other diseases caused by cell proliferation. Abnormal, HDM2-associated disease, or intermittent P53-associated disease Invention today revealed a method for the use of a compound acting as an anti-HDM2 protein, to treat or prevent cancer, other diseases caused by cell proliferation. Unusual, HDM2-associated disease, or intermittent P53-associated disease.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH102404A true TH102404A (en) | 2010-06-30 |
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