SV1999000042A - PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED-1H-INDOL-3 GLIOXAMIDES REF. X-12932 - Google Patents

PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED-1H-INDOL-3 GLIOXAMIDES REF. X-12932

Info

Publication number
SV1999000042A
SV1999000042A SV1999000042A SV1999000042A SV1999000042A SV 1999000042 A SV1999000042 A SV 1999000042A SV 1999000042 A SV1999000042 A SV 1999000042A SV 1999000042 A SV1999000042 A SV 1999000042A SV 1999000042 A SV1999000042 A SV 1999000042A
Authority
SV
El Salvador
Prior art keywords
preparation
glioxamides
indol
ref
substituted
Prior art date
Application number
SV1999000042A
Other languages
Spanish (es)
Inventor
Richard Duane Miller
Edward Francis Plocharczyk
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SV1999000042A publication Critical patent/SV1999000042A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ESTE INVENTO SE REFIERE A UN PROCESO PARA PREPARAR CIERTOS GLOXIAMIDAS-4-SUBSTITUIDOS UTILES PARA INHIBIR LA EMISION INTERMEDIADA DE SPLA2 DE ACIDOS GRASOS PARA CONDICIONES TALES COMO EL SHOCK SEPTICO E INTERMEDIOS UTILES EN LA PREPARACION DE DICHOS COMPUESTOS.THIS INVENTION REFERS TO A PROCESS TO PREPARE CERTAIN USEFUL GLOXIAMIDES-4-SUBSTITUTES TO INHIBIT THE INTERMEDIATE EMISSION OF SPLA2 OF FATTY ACIDS FOR CONDITIONS SUCH AS SEPTIC SHOCK AND USEFUL INTERMEDIATES IN THE PREPARATION OF SUCH COMPOUNDS.

SV1999000042A 1998-10-09 1999-04-15 PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED-1H-INDOL-3 GLIOXAMIDES REF. X-12932 SV1999000042A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10360498P 1998-10-09 1998-10-09

Publications (1)

Publication Number Publication Date
SV1999000042A true SV1999000042A (en) 2000-04-11

Family

ID=22296053

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1999000042A SV1999000042A (en) 1998-10-09 1999-04-15 PROCESS FOR THE PREPARATION OF 4-SUBSTITUTED-1H-INDOL-3 GLIOXAMIDES REF. X-12932

Country Status (11)

Country Link
EP (1) EP1119549A4 (en)
JP (1) JP2002527421A (en)
AR (1) AR015766A1 (en)
AU (1) AU3564499A (en)
CA (1) CA2347718A1 (en)
CO (1) CO5021230A1 (en)
DZ (1) DZ2771A1 (en)
PE (1) PE20000429A1 (en)
SV (1) SV1999000042A (en)
TW (1) TW472041B (en)
WO (1) WO2000021929A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ876400A0 (en) * 2000-07-14 2000-08-03 University Of Queensland, The Compositions and method of using them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6032769A (en) * 1983-08-02 1985-02-19 Sagami Chem Res Center Preparation of 4-hydroxyindole derivative
CO4370099A1 (en) * 1994-04-01 1996-10-07 Lilly Co Eli 1H-INDOL-3-GLIOXYLAMIDES sPLA2 INHIBITORS
CA2279211A1 (en) * 1997-02-20 1998-08-27 Shionogi & Co., Ltd. Indole dicarboxylic acid derivatives

Also Published As

Publication number Publication date
CA2347718A1 (en) 2000-04-20
EP1119549A1 (en) 2001-08-01
AR015766A1 (en) 2001-05-16
JP2002527421A (en) 2002-08-27
CO5021230A1 (en) 2001-03-27
PE20000429A1 (en) 2000-05-23
TW472041B (en) 2002-01-11
EP1119549A4 (en) 2003-01-29
AU3564499A (en) 2000-05-01
DZ2771A1 (en) 2003-12-01
WO2000021929A1 (en) 2000-04-20

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Legal Events

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