SU827064A1 - Method of prophylaxis endogenic infecting at acute leukosis - Google Patents

Method of prophylaxis endogenic infecting at acute leukosis Download PDF

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Publication number
SU827064A1
SU827064A1 SU792769498A SU2769498A SU827064A1 SU 827064 A1 SU827064 A1 SU 827064A1 SU 792769498 A SU792769498 A SU 792769498A SU 2769498 A SU2769498 A SU 2769498A SU 827064 A1 SU827064 A1 SU 827064A1
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USSR - Soviet Union
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acute
endogenic
leukosis
infecting
prophylaxis
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SU792769498A
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Russian (ru)
Inventor
Татьяна Васильевна Голосова
Вера Александровна Мартынова
Тамара Васильевна Толкачева
Евгений Михайлович Абакумов
Татьяна Леонидовна Котт
Original Assignee
Центральный Научно-Исследовательскийордена Ленина И Ордена Трудового Красногознамени Институт Гематологии И Переливаниякрови
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Priority to SU792769498A priority Critical patent/SU827064A1/en
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Description

бйфйдббактёрий высевались Ё количествах 10,0 Ig/r.Byfidbbacter were sown in quantities of 10.0 Ig / r.

Пример 4. У больного 3. 20 лет с острым лимфобластным лейкозом отмечено сниженное количество нормальных представителей бифидобактерий до 6,0 Ig/r и высевалось большое количество синегнойной палочки до 7,0 Ig/r. Этому больному сначала назначали синегнойиый фаг (2 курса ), после подавлени  роста Ps aeruginosa больной получал бифидумбактерин в течение 21 дн . После приема больным биологических препаратов отмечено исчезновение из кишечника синегнойной палочки и увеличение бифидобактерий до 8,0 Ig/r. Example 4. Patient 3. For 20 years with acute lymphoblastic leukemia, there was a reduced number of normal representatives of bifidobacteria up to 6.0 Ig / r and a large number of Pseudomonas bacillus was seeded to 7.0 Ig / r. This patient was first prescribed blue-necked phage (2 courses), after suppressing the growth of Ps aeruginosa, the patient received Bifidumbacterin for 21 days. After the patient received biological preparations, the disappearance of the pseudomonas bacillus and an increase in bifidobacteria to 8.0 Ig / r were noted.

Если нар ду со снижением бифидобактерий отмечены нарушени  и в коли-флоре, то вместо бифидумбактерина больным назначали прием бификола.If, along with a decrease in bifidobacteria, disturbances were also noted in the coli-flora, then instead of bifidumbacterin, patients were prescribed bifikol.

У всех больных, получавших бактерийные препараты в период проведени  цитостатической терапии, наблюдали восстановление нормальной флоры кишечника, инфекционные осложнени  у наблюдаемой группы больных не отмечались.In all patients who received bacterial preparations during the period of cytostatic therapy, restoration of the normal intestinal flora was observed; no infectious complications were observed in the observed group of patients.

Предлагаемый способ способствует востановлению экологического равновеси  кишечного биоценоза физиологическим путем, снижает возможность эндогенного инфицировани  организма больного наиболее опасными грамотрицательными микроорганизмами (синегнойиа  палочка, протей и др.), уменьшает риск возникновени  инфекционных осложнений у больных острыми лейкозами , которые в 70% случаев  вл ютс  непосредственной причиной гибели больных в период медикаментозной гипоплазии.The proposed method contributes to the restoration of the ecological balance of the intestinal biocenosis by physiological means, reduces the possibility of endogenous infection of the patient's body with the most dangerous gram-negative microorganisms (blue-collar, proteus, etc.), reduces the risk of infectious complications in patients with acute leukemia, which in 70% of cases are the direct cause death of patients in the period of drug hypoplasia.

Claims (1)

1. Preisler Н. D., Goldstein I. М. et al. Gastrointestinal sterelization in the Treatement of Patients with Aeute Lenkemia. Caucer (Philad). 1970, 26, 5, 1076, 1981.1. Preisler N. D., Goldstein I. M. et al. Gastrointestinal Sterelization in the Treatement of Patients with Aeute Lenkemia. Caucer (Philad). 1970, 26, 5, 1076, 1981.
SU792769498A 1979-05-17 1979-05-17 Method of prophylaxis endogenic infecting at acute leukosis SU827064A1 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4123330A1 (en) * 1991-07-15 1993-01-21 Gerhard Netz Per-anal bacteria introduction system for regeneration of bowel bacteria - includes accommodating bacteria in water-soluble, pref. gelatin casing prior to insertion via sleeve
US6942858B1 (en) * 1996-04-15 2005-09-13 Nymox Corporation Compositions containing bacteriophages and methods of using bacteriophages to treat infections

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4123330A1 (en) * 1991-07-15 1993-01-21 Gerhard Netz Per-anal bacteria introduction system for regeneration of bowel bacteria - includes accommodating bacteria in water-soluble, pref. gelatin casing prior to insertion via sleeve
US6942858B1 (en) * 1996-04-15 2005-09-13 Nymox Corporation Compositions containing bacteriophages and methods of using bacteriophages to treat infections

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