SU789576A1 - Echo serotype 14 n 3081 virus strain for producing diagnostic serum - Google Patents
Echo serotype 14 n 3081 virus strain for producing diagnostic serum Download PDFInfo
- Publication number
- SU789576A1 SU789576A1 SU782617487A SU2617487A SU789576A1 SU 789576 A1 SU789576 A1 SU 789576A1 SU 782617487 A SU782617487 A SU 782617487A SU 2617487 A SU2617487 A SU 2617487A SU 789576 A1 SU789576 A1 SU 789576A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- serum
- strains
- strain
- echo
- serotype
- Prior art date
Links
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Description
1one
Изобретение относитс к вирусологии и касаетс получени диагностических сывороток.This invention relates to virology and relates to the production of diagnostic sera.
Предложенный штамм новый и в научно-технической и патентной литературе не описан.The proposed strain is new and in the scientific, technical and patent literature is not described.
Целью изобретени вл етс получение высокоактивной и специфической сыворо.тки.The aim of the invention is to obtain highly active and specific serum.
Итамм № 3081 вируса ECHO серотипа 14 дл получени диагностической сыворотки вьщелен в институте им.Пастера и хранитс в Государственной коллекции вирусов Института вирусологии им. Д.И.Ивановского под но мером ГКВ 1635,Etam No. 3081 of serotype 14 ECHO virus for diagnostic serum was obtained at the Pasteur Institute and stored in the State Collection of Viruses of the Institute of Virology. D.I. Ivanovsky under the order of STB 1635,
Культурно-морфологические признаки .Cultural and morphological features.
Морфологи типична дл энтеровирусов .Morphology is typical for enteroviruses.
Устойчив к действию эфира, обладает повышенной устойчивостью к прогреванию при 50°С в присутствии солей магни и кальци .Resistant to the action of ether, has a high resistance to heating at 50 ° C in the presence of magnesium and calcium salts.
Чувствителен к первичным фибробластам эмбриона человека и перевиваемым диплоидным клеткам легкого эмбриона человека. Четко выражен цитопатогенный эффект.Sensitive to primary human embryo fibroblasts and transplantable diploid human lung embryo cells. A clearly pronounced cytopathogenic effect.
Титр инфекциозности дл культуры , тканей 5 ед ТСД 50/мл.Infectious titer for culture, tissue 5 units TSD 50 / ml.
Гемагглютинируюцей активностью в отношении эритроцитов обезь н,кур,Hemagglutination activity against erythrocytes monkeys, chickens,
5 барана и человеческих О-групп не обладает ..5 ram and human O-groups does not possess ..
Антигенные свойства. Стимулирует продукцию специфических антител в организме кроликов.Antigenic properties. Stimulates the production of specific antibodies in the body of rabbits.
10 Имеет широкий спектр антигенной активности и специфичности.10 Has a wide range of antigenic activity and specificity.
Сыворотка к штамму нейтрализует штаммы с различной антигенной структурой .Serum to strain neutralizes strains with different antigenic structure.
5 Пример использование штамма, Д.1 получени сыворотки.5 An example of the use of a strain, E.1 of obtaining serum.
Дл приготовлени сыворотки кроликов весом 2,5-3,0 кг иммунизируют 3-кратно антигенным вариантом ECHOTo prepare rabbit serum weighing 2.5-3.0 kg, they are immunized 3 times with antigenic variant ECHO.
20 вируса серотипа 14/3081 с интервалом в 7 дней. В 1-ую и 2-ую недели антиген ввод т внутриьчышечно в правую и левую конечности по 2,5 мл и внутривенно по 1 мл на 3-ю неделю 1 мл20 virus serotype 14/3081 with an interval of 7 days. In the 1st and 2nd weeks, the antigen is administered intracellularly in the right and left extremities of 2.5 ml and 1 ml intravenously for the 3rd week of 1 ml
25 внутривенно. На 10-ый день после25 intravenously. On the 10th day after
последней иммунизации животных обескровливают и готов т сыворотку. Активность сыворотки определ ют в реакции нейтрализации в культуреThe last immunization of animals is exsanguinated and serum is prepared. Serum activity is determined by neutralization in culture.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU782617487A SU789576A1 (en) | 1978-05-22 | 1978-05-22 | Echo serotype 14 n 3081 virus strain for producing diagnostic serum |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU782617487A SU789576A1 (en) | 1978-05-22 | 1978-05-22 | Echo serotype 14 n 3081 virus strain for producing diagnostic serum |
Publications (1)
Publication Number | Publication Date |
---|---|
SU789576A1 true SU789576A1 (en) | 1980-12-23 |
Family
ID=20765433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU782617487A SU789576A1 (en) | 1978-05-22 | 1978-05-22 | Echo serotype 14 n 3081 virus strain for producing diagnostic serum |
Country Status (1)
Country | Link |
---|---|
SU (1) | SU789576A1 (en) |
-
1978
- 1978-05-22 SU SU782617487A patent/SU789576A1/en active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Bradburne et al. | Coronavirus antibody titres in sera of healthy adults and experimentally infected volunteers | |
Coleman et al. | The HONG KONG/68 influenza A2 variant | |
Cook et al. | Antigenic differentiation of strains of turkey rhinotracheitis virus using monoclonal antibodies | |
Thomson et al. | Serological Detection of Equid Herpesvirus1 Infections of the Respiratory Tract | |
Campbell et al. | Fowl plague virus from man | |
Beare et al. | RECOMBINANT INFLUENZA-A VIRUSES AS LIVE VACCINES FOR MAN: Report to the Medical Research Council's Committee on Influenza and other Respiratory Virus Vaccines | |
Ludwig et al. | Biology and neurobiology of Borna disease viruses (BDV), defined by antibodies, neutralizability and their pathogenic potential | |
US4009258A (en) | Influenza vaccine containing a recombinant, antigenically hybridized virus and method of using the same | |
Örvell et al. | Further studies on the immunologic relationships among measles, distemper, and rinderpest viruses | |
Kaplan et al. | Pathogenesis of rabies in immunodeficient mice | |
Baxby et al. | Characteristics of a new poxvirus isolated from Indian buffaloes | |
Finberg et al. | Host immune response to reovirus: CTL recognize the major neutralization domain of the viral hemagglutinin. | |
Marennikova et al. | Susceptibility of some rodent species to monkeypox virus, and course of the infection | |
Ignjatovic et al. | Structural proteins of avian infectious bronchitis virus: role in immunity and protection | |
De Boer et al. | Prevalence of antibodies to equine viruses in the Netherlands | |
Bastien et al. | Immunization with a peptide derived from the G glycoprotein of bovine respiratory syncytial virus (BRSV) reduces the incidence of BRSV-associated pneumonia in the natural host | |
Sweet et al. | The pregnant ferret as a model for studying the congenital effects of influenza virus infection in utero: infection of foetal tissues in organ culture and in vivo. | |
SU789576A1 (en) | Echo serotype 14 n 3081 virus strain for producing diagnostic serum | |
Hofstad | Immunity following aerosol exposure to high-embryo-passage avian infectious bronchitis virus | |
Laver et al. | Diversity of the antibody response to the different antigenic determinants on the hemagglutinin subunits of influenza viruses | |
Nerome et al. | Isolation and serological characterization of influenza A viruses from birds that were dead on arrival at Tokyo airport | |
Ueda et al. | Immunological relationship between herpes simplex virus and B virus | |
US3422187A (en) | Influenza vaccines and process for their manufacture | |
MacDonald | Haemagglutination with the Virus of Murray Valley Encephalitis (MVE) | |
Lief et al. | Antigenic variation among parainfluenza type 1 (Sendai) viruses: analysis of 6/94 virus |