SU787407A1 - Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines - Google Patents

Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines Download PDF

Info

Publication number
SU787407A1
SU787407A1 SU792730183A SU2730183A SU787407A1 SU 787407 A1 SU787407 A1 SU 787407A1 SU 792730183 A SU792730183 A SU 792730183A SU 2730183 A SU2730183 A SU 2730183A SU 787407 A1 SU787407 A1 SU 787407A1
Authority
SU
USSR - Soviet Union
Prior art keywords
methyl
catalyst
yield
increase
dicyanopyridines
Prior art date
Application number
SU792730183A
Other languages
Russian (ru)
Inventor
Борис Викторович Суворов
Искра Ивановна Кан
Людмила Кузминична Глубоковских
Сергей Владимирович Берстенев
Original Assignee
Институт химических наук АН Казахской ССР
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт химических наук АН Казахской ССР filed Critical Институт химических наук АН Казахской ССР
Priority to SU792730183A priority Critical patent/SU787407A1/en
Application granted granted Critical
Publication of SU787407A1 publication Critical patent/SU787407A1/en

Links

Landscapes

  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Description

II

Изобретение относитс  к усовершен ствованному способу получени  2,6-дицианпиридина и 2-метил-6-ч1ианпириаина, которые наход т широкое применение в синтезе биологически активных соединений и в производстве полимерных материалов .The invention relates to an improved process for the preparation of 2,6-dicyanopyridine and 2-methyl-6-h1-pyrianaine, which are widely used in the synthesis of biologically active compounds and in the manufacture of polymeric materials.

Известен способ получени  2,6-аицианпиридина и 2-метил-6- 1ианпириаина окислительным аммонолизом 2,6- 1утиди- на в присутствии окисного ванадиево-се- ребр ного катализатора при 410-470 С. Максимальные выходы указанных нитрилов-составл ет 16 и 50% соответственно , счита  на прореагировавший 2,6-лутицин (14 и 26% в расчете на поданное сырье). Суммарный выход обоих нитрилов в одном цикле не превышает 36% |l.A known method for producing 2,6-acyanopyridine and 2-methyl-6-1-pyriana is by oxidative ammonolysis of 2,6-1-utidine in the presence of oxide vanadium-silver catalyst at 410-470 C. The maximum yields of these nitriles are 16 and 50%, respectively, counting on the reacted 2,6-lutycin (14 and 26%, calculated on the feedstock). The total yield of both nitriles in one cycle does not exceed 36% | l.

Недостатками этого способа  вл ютс  низкий выход целевых продуктов и применение дорогого и сложного в изготовлении катализатора.The disadvantages of this method are the low yield of the target products and the use of expensive and difficult to manufacture catalyst.

Наиболее -близким к предлагаемому  вл етс  способ получени  2,6-дициан-The closest to the proposed method is the preparation of 2,6-dicyanol

И 2-метил-6-цианпиридинов окислительным аммонолизом 2,6-лутидина над окисным ванадиево -титановым катализатором ( 2.0. , TiO2. ) при 350-370 С. Выход 2,6-д циaнm pидинa 40-60%, мононитрила 7-19%, в расчете на поданный 2,6-ллутидин. Суммарный выход нитрилов за 1 цикл 58-67% 2.And 2-methyl-6-cyanpyridines by oxidative ammonolysis of 2,6-lutidine over vanadium oxide-titanium catalyst (2.0., TiO2.) At 350-370 C. The yield of 2,6-d cyanide is 40-60%, mononitrile 7- 19%, based on 2,6-llutidine. The total yield of nitriles per 1 cycle is 58-67% 2.

Однако дранный способ характеризуетс  недостаточно высоким выходом 2,6-дицианпиридина и низким выходом 2-ме- тш1-6-41ианпиридина.However, the durr method is characterized by an insufficiently high yield of 2,6-dicyanopyridine and a low yield of 2-mash 1-6-41 yanopyridine.

Шль изобретени  - увеличение выхода целевых продуктов и повышение селективности процесса.The invention is an increase in the yield of the target products and an increase in the selectivity of the process.

Поставленна , цель достигаетс  тем, что ок ислительный аммонолиз 2,6-глутидина провод т в присутствии катализатораплавленой п тиокиси ванади  при 320380С .The goal set is achieved by the fact that the oxidative ammonolysis of 2,6-glutidine is carried out in the presence of a catalyst with fused vanadium pentoxide at 3203 ° C.

При 380 С и времени контакта 0,5 с процессе направл етс  в сторону обраг(о- вани  2,6-дицианпиридина, его выходAt 380 ° C and a contact time of 0.5 s, the process is directed towards the treatment (formation of 2,6-dicyanopyridine, its output

Claims (2)

Формула изобретенияClaim Способ получения 2-метил-6-циан— и 2,6-дицианпиридинов путем окислительного аммонолиза 2,6-лутидина в присутствии катализатора, при повышенной температуре, отличающийся тем, что, с целью.увеличения выхода целевых продуктов и повышения селективности процесса, в качестве катализатора используют плавленную пятиокись ванадия и процесс проводят при 320-380°С.A method of producing 2-methyl-6-cyan- and 2,6-dicyanpyridines by oxidative ammonolysis of 2,6-lutidine in the presence of a catalyst at elevated temperature, characterized in that, in order to increase the yield of target products and increase the selectivity of the process, fused vanadium pentoxide is used as a catalyst and the process is carried out at 320-380 ° C. 50 Источники информации, принятые во внимание при экспертизе50 Sources of information taken into account in the examination 1. Авторское свидетельство СССР № 555096, кл. С 07D 213/60, 1977.1. USSR author's certificate No. 555096, cl. C 07D 213/60, 1977. 2. Авторское свидетельство СССР 55' № 548602, кл. С 07 D 213/57, 1977 (прототип).2. USSR Copyright Certificate 55 'No. 548602, cl. C 07 D 213/57, 1977 (prototype). Тираж 495 ПодписноеCirculation 495 Subscription Филиал ППП 'Патент*, г. Ужгород, уп. Проектная, 4Branch of PPP 'Patent *, Uzhhorod, unitary enterprise. Project, 4
SU792730183A 1979-02-23 1979-02-23 Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines SU787407A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU792730183A SU787407A1 (en) 1979-02-23 1979-02-23 Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU792730183A SU787407A1 (en) 1979-02-23 1979-02-23 Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines

Publications (1)

Publication Number Publication Date
SU787407A1 true SU787407A1 (en) 1980-12-15

Family

ID=20812478

Family Applications (1)

Application Number Title Priority Date Filing Date
SU792730183A SU787407A1 (en) 1979-02-23 1979-02-23 Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines

Country Status (1)

Country Link
SU (1) SU787407A1 (en)

Similar Documents

Publication Publication Date Title
MX7465E (en) IMPROVED PROCEDURE FOR OBTAINING CATALYSTS OR CATALYST SUPPORTS BASED ON TITANIUM OXIDE FOR THE CLAUS PROCESS OF SULFUR SYNTHESIS
GB981005A (en) Process for preparing nitriles
PT73111B (en) Process for preparing new para-substituted 3-phenoxy-1-alkylamino-propanol-2-p having beta receptor blocking properties
FR2362117A1 (en) NEW DERIVATIVES OF 2,4,6-TRIIODOBENZOIC ACID USABLE AS A CONTRAST MEDIA AND THEIR PREPARATION PROCESS
OA06146A (en) N-phenyl-N '- (2'-chloro-6-fluoro-benzoyl) -ureas, their production process and their application as insecticides.
ES2075315T3 (en) PROCEDURE FOR THE PREPARATION OF ACIDS (6S) - AND (6R) -TETRAHYDROPHOLIC.
SU787407A1 (en) Method of preparing 2-methyl-6-cyano- and 2,6-dicyanopyridines
FR2436144A1 (en) NOVEL AURON DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE AS PHARMACEUTICALS
Bacon et al. Some amides and esters of fluoroacetic acid
OA04770A (en) New carbonic acid derivatives of 2-mercapto-4,5-dichlorothiazole, their preparation process and their application as herbicides.
SU1227623A1 (en) Method of producing terenaphthalonitrile
ATE1707T1 (en) PROCESS FOR THE PREPARATION OF THIOCHLOROFORMATES.
SU843992A1 (en) Method of obtaining gallic acid
SU676590A1 (en) 2,5-dicyanpyridine producing method
SU659093A3 (en) Method of obtaining salts of 2-(dimethylcarbamoylimino)-benzthiazolinide-3
SU801874A1 (en) Catalyst for non-complete oxidation of propane
SU670569A1 (en) Method of producing 4-pyridineacrolein
SU690002A1 (en) Method of preparing 4-methoxy-1,2-naphthoquinone
SU566454A1 (en) 2-(alpha-phenyl amino-beta-p-chlorostyryl)-or 2-(alpha-phenyl amino-beta-p-methylstyryl) quinoxalone-3, exhibiting antiinflammatory activity
DE59000005D1 (en) METHOD FOR PRODUCING A MIXTURE OF OXIDATION PRODUCTS OF SACCHAROSE AND THE USE THEREOF.
SU727217A1 (en) Single-shot multivibrator
RU93015431A (en) METHOD OF OBTAINING 2-CYANPYRAZINE
SU432097A1 (en) Method of producing trimetaphosphate
ZA88640B (en) Novel imidazo-and triazolothiadiazines,a process for the preparation thereof,medicaments containing same,and the use thereof,and some intermediates formed in the preparation of the compounds mentioned
JPS625420B2 (en)